Researchers have narrowed down a genetic region associated with autism to one protein, cadherin 8, that helps bind cells together, according to a study published online in October in the Journal of Medical Genetics. This is the first time CDH8, the gene that encodes this protein, has been associated with autism.
Spectrum: Autism Research News
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Stem cell studies show that a mutation in the neuroligin-4 gene disrupts the normal development of synapses, the junction between neurons, according to unpublished data shown Sunday at the Society for Neuroscience annual meeting in San Diego.
Siblings of children with autism who show no signs of the disorder may be compensating with increased activity in two brain regions that detect social cues, according to results presented yesterday at the Society for Neuroscience annual meeting in San Diego.
A combination approach may hold promise for treating repetitive motor behaviors, such as those seen in people with autism, according to research presented yesterday at the Society for Neuroscience annual meeting in San Diego.
A new mouse model for Rett syndrome shows that disrupting a single brain messenger can produce nearly all of the characteristic features of the syndrome, researchers report today in Nature.
Chromosome 15 may harbor one or more risk genes for autism, according to a new study of multigenerational inheritance in Utah. Researchers have gathered data on family pedigrees stretching back as far as nine generations, with up to five family members affected by the disorder.
Infection early in pregnancy is more harmful to the fetus than at later stages, triggering brain and behavioral changes in the offspring similar to those seen in people with schizophrenia, according to two mouse studies published in October. A third study suggests that exercise can mitigate some of these effects.
An antipsychotic drug often prescribed to treat irritability in children with autism may be more helpful — and cause fewer side effects — depending on an individual’s genetic make-up.
Loss of activity of FOXP1, a member of a family of genes that regulate gene expression, leads to general behavioral defects, including delays in language, according to a study published in November in The American Journal of Human Genetics.