Deleting a neuronal protein associated with autism causes oxidative stress — characterized by an excess of free radicals — which has been linked to diseases such as diabetes and Alzheimer’s, according to new research in worms. The results were presented yesterday at a poster session at the Society for Neuroscience meeting in Chicago.
Spectrum: Autism Research News
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Mice carrying an autism-associated mutation show impaired social interactions and dramatic changes in brain size when their immune systems are activated, according to research presented yesterday at a poster session at the Society for Neuroscience meeting in Chicago.
After a Monday afternoon poster session at the Society for Neuroscience meeting in Chicago, Noboru Hiroi talked about the challenges of following up human genetic findings in the mouse.
National Institutes of Health director Francis Collins talks about the agency’s upcoming plans for “beefing up” autism research, including more than $100 million each year in grants for the field.
Adolescents who carry certain common variants in a gene associated with autism — whether they have the disorder or not — show abnormal connectivity between brain regions, according to unpublished data presented at the Society for Neuroscience meeting in Chicago.
Mice missing FKBP12, a gene involved in a cancer pathway, show repetitive behavior and an impaired ability to socialize with other mice, and could be used to study autism, according to unpublished results presented at a poster session today at the Society for Neuroscience meeting.
Tracy Bale, associate professor of neuroscience at the University of Pennsylvania, talks about what she calls her “big soapbox issue”: the fallacious idea of a true animal model for a human psychiatric disease — and the pitfalls of over-interpreting rodent behavior.