The Simons Simplex Collection (SSC), a database of genetic and clinical information from families that include one child with autism, has gathered data from more than 2,000 different families, researchers report in the October issue of Neuron.
Spectrum: Autism Research News
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
The first genome-wide linkage analysis of more than 1,200 families has identified regions implicated in autism as originating from either the paternal or maternal copies of chromosomes.
SHANK1 — a member of a family of proteins linked to autism — does not cause autism-like social deficits when mutated in mice, according to a study published online in September in Brain Research.
Children with Williams syndrome are chatty, have rich vocabularies and love to tell stories. Yet they have trouble learning certain complex rules of grammar, according to a study published in the Journal of Speech, Language and Hearing Research.
People with autism show differences in the levels of various gene products compared with their unaffected siblings, according to a study published online in September in Brain Research.
A tumor suppressor best known for its role in colorectal cancer plays a critical role in forming connections between neurons, according to a study in the August 18 issue of the Journal of Neuroscience.