Researchers have identified a rare genetic variant linked to autism in DLX1, a gene that regulates the growth of neurons, they reported in December in the American Journal of Medical Genetics.
Spectrum: Autism Research News
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
High levels of serotonin in the womb may up the risk of autism in the child, according to a study published in December in the American Journal of Medical Genetics.
Mice exposed to an epilepsy drug show several features of autism, including abnormal social interactions, repetitive behaviors and patterns of super-fast brain waves, called gamma oscillations, according to a study published 15 December in Biological Psychiatry.
Accounting for gender increases the power of family-wide studies linking genetic mutations with autism, according to a study published in December in Molecular Psychiatry. The researchers use this approach to identify two candidate genes for the disorder.
Using tricks of genetic engineering, researchers in Taiwan have created the first comprehensive map of the myriad neuronal connections in the fruit fly brain. The findings appeared 11 January in Current Biology.
Relatives of individuals with autism recognize faces and emotions better than people with autism do, but not as well as typically developing controls do, according to a study published in December in Autism Research.
Copy number variations, or CNVs — duplications or deletions of DNA segments — can influence the expression of unrelated genes on the same chromosome, according to a study published in November in PLOS Biology.
Scientists have created mice that carry mutations in SHANK3, one of the strongest candidate genes for autism. The animals have behavioral and neurobiological features reminiscent of autism, researchers reported 17 December in Molecular Autism.