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Spectrum: Autism Research News

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Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

March 2011

Studies implicate gut bacteria in autism

by  /  7 March 2011

Researchers are exploring the possibility that gastrointestinal bacteria may influence brain development and play a role in autism.

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Strategic update

by  /  4 March 2011

The Interagency Autism Coordinating Committee has released an updated list of priorities for government-funded autism research.

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Researchers catalog crucial complex in neurons

by  /  2 March 2011

Researchers have identified nearly 1,500 proteins present in the postsynaptic density — a complex collection of proteins that enables quick and flexible signaling across the brain. The results were published 14 January in Nature Neuroscience.

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Molecular mechanisms: Inflamed placenta linked to schizophrenia, autism

by  /  2 March 2011

Infection with swine flu in early pregnancy causes inflammation in the placenta, and raises the risk of schizophrenia and autism in the offspring, according to a study published in January in Neuropharmacology.

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Active brains

by  /  1 March 2011

Studies of healthy infants may help identify early risk factors for autism by establishing new developmental milestones.

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February 2011

Matthew State: Bridging the gap between bench and bedside

by  /  24 February 2011

Matthew State is both a dedicated clinician and a world-class geneticist, but his diplomatic style is a relic of his former adventures in politics.

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Genetics: Study reexamines role of 16p11.2 in autism

by  /  23 February 2011

Duplication or deletion of 16p11.2 — a much-studied chromosomal region with a strong association with autism — is present in 0.76 percent of people with the disorder, according to a meta-analysis published February in Genetics in Medicine.

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Database organizes multiple mouse models

by  /  23 February 2011

A genetic database of autism genes, called Autism Database, or AutDB, details curated information for more than 200 mouse models of autism, according to a report in the January BMC Genomics.

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Cognition and behavior: Serotonin pathway affects mouse behavior

by  /  22 February 2011

Mice that lack the gene for integrin β3, or ITGB3 — which regulates the levels of serotonin in the blood — groom themselves frequently and show less interest in stranger mice compared with controls, according to a study published in February in Autism Research as part of a special issue on mouse models in autism.

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Genetic background alters behavior of fragile X mice

by  /  21 February 2011

Six strains of mice lacking a gene associated with fragile X syndrome show radically different behaviors though they share the same mutation, researchers reported in January in Autism Research.

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