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Spectrum: Autism Research News

Tag: tuberous sclerosis

November 2011

Mouse models point to early troubles in tuberous sclerosis

by  /  28 November 2011

The brain abnormalities characteristic of tuberous sclerosis may begin early in development and involve malfunctioning of neuronal precursors, according to studies of two different mouse models of the disorder published in October.

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July 2011

Reclassification of Rett syndrome diagnosis stirs concerns

by  /  4 July 2011

A plan by an American Psychiatric Association revision committee to remove Rett syndrome from the Diagnostic and Statistical Manual of Mental Disorders (DSM) has sparked concern among some parents and researchers. But proponents of the change say the plan has been widely misunderstood, and their goal is better treatment for people with the neurodevelopmental disorder.

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June 2011

Clinical research: Photographs reveal unusual physical features

by  /  21 June 2011

Photographs that reveal minor physical abnormalities often seen in children with autism or other developmental disabilities could be useful as a first screen for autism, according to a study published 24 May in Autism.

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Protein networks link different forms of autism, study says

by  /  13 June 2011

Researchers have identified hundreds of previously unknown connections between proteins involved in autism spectrum disorders, according to a report published last week in Science Translational Medicine.

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May 2011

Scientists probe puzzling overlap of epilepsy and autism

by  /  12 May 2011

Large studies on the epidemiology and genetics of epilepsy and autism have uncovered commonalities between the two disorders. But scientists are only beginning to untangle the biological roots of the overlap.

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April 2011

Genetics: Seizures link autism, tuberous sclerosis

by  /  22 April 2011

Frequent seizures up the risk of having both autism and the related disorder tuberous sclerosis, according to a study published 15 March in Neurology.

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November 2010

Tuberous sclerosis mice have fewer synaptic proteins

by  /  17 November 2010

A study of mice with tuberous sclerosis — a single-gene disorder that is related to autism — suggests that most forms of autism share a common feature: an imbalance of proteins at the synapse, the junction between neurons. The work was presented Monday at the Society for Neuroscience annual meeting in San Diego.

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September 2010

Studies tie fragile X syndrome to famous cancer pathway

by  /  23 September 2010

A drug that interferes with a biochemical pathway important in cancer can reverse some brain defects in mouse models of fragile X syndrome, according to a study published 11 August in the Journal of Neuroscience.

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August 2010

Power shortage

by  /  5 August 2010

One of the largest genome-wide association studies for autism spectrum disorders, reported last week in Human Molecular Genetics, allows only one definitive conclusion: it isn’t large enough.

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June 2010

Simple pathway

by  /  24 June 2010

A study of a rare form of epilepsy found in Amish groups adds heft to the idea that mTOR — a much-studied hub in a massive network of brain cell proteins — is an important biochemical player in autism.

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