An artificial-intelligence algorithm designed to analyze behavior has learned to recognize six genetic disorders associated with autism, according to a report published 11 February in Molecular Autism. The algorithm could be used to hone the search for autism’s genetic underpinnings.
Spectrum: Autism Research News
Tag: tuberous sclerosis
Rapamycin, a drug given to suppress immune rejection after transplants, improves social behavior in mice with features of autism, reports a study published in the January issue of Brain Research Bulletin.
Roughly one-quarter of people with neurofibromatosis type 1 — one of a family of rare disorders that show enhanced signaling in a cancer-related pathway — also have autism, according to a study published in December in Pediatrics.
Boys with tuberous sclerosis complex, an autism-related disorder, have more disorganized nerve fibers in some regions of the brain than do girls with the disorder, according to unpublished work presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.
About one in four people diagnosed with a group of rare disorders have autism, according to a study published 7 October in the Journal of Medical Genetics. The disorders all affect a single cancer-related pathway, driven by a protein called RAS.
The autism-like features seen in related neurological disorders may be the result of intellectual disability and not a shared underlying biology, says Alan Packer.
The mutation that causes tuberous sclerosis complex, an autism-related disorder, may disable calming signals in the brain, leading to hyperactive neurons, according to a study published 8 May in Neuron.
Deleting both copies of a gene linked to tuberous sclerosis complex, an autism-related disorder, in only a subset of brain cells recapitulates many of the disorder’s symptoms in mice, according to a study published 9 May in Neuron.