Two studies published in the past two months provide new clues to when and how the cerebellum contributes to autism.
Spectrum: Autism Research News
Tag: tuberous sclerosis
Triggering an immune defense in newborn male mice missing a copy of TSC2, a gene linked to autism, impairs the mice’s social memory.
David and Bernardo Sabatini, brothers born just a year and a half year apart, invent their way to answering big questions about autism.
Mice with the mutations linked to tuberous sclerosis make too little protein in their brains — a finding that contradicts a leading theory about the condition.
Despite social media rumors, a British children’s television show does not cause autism; childhood anesthesia is not tied to autism risk; and an adult on the spectrum reaches a haunting milestone
The drug rapamycin, which is in clinical trials as a treatment for tuberous sclerosis, may exacerbate features of fragile X syndrome, another condition related to autism.
Infants who have neurofibromatosis, a genetic condition linked to autism, show motor difficulties and communication delays at 10 months of age.
A drug called rapamycin prevents seizures in a mouse model of the autism-related condition tuberous sclerosis complex.
Some genes linked to autism regulate the production of proteins at neuronal junctions, suggesting that disrupted protein synthesis contributes to the condition.