Mice with the mutations linked to tuberous sclerosis make too little protein in their brains — a finding that contradicts a leading theory about the condition.
Spectrum: Autism Research News
Tag: tuberous sclerosis
Despite social media rumors, a British children’s television show does not cause autism; childhood anesthesia is not tied to autism risk; and an adult on the spectrum reaches a haunting milestone
The drug rapamycin, which is in clinical trials as a treatment for tuberous sclerosis, may exacerbate features of fragile X syndrome, another condition related to autism.
Infants who have neurofibromatosis, a genetic condition linked to autism, show motor difficulties and communication delays at 10 months of age.
A drug called rapamycin prevents seizures in a mouse model of the autism-related condition tuberous sclerosis complex.
Some genes linked to autism regulate the production of proteins at neuronal junctions, suggesting that disrupted protein synthesis contributes to the condition.
A movement to ban valproate during pregnancy gains a foothold in France, people with auditory hallucinations seek to demedicalize the experience, and adults on the spectrum speak out.
Children with tuberous sclerosis who have seizures as infants are particularly likely to also have developmental delay and autism features.