Mouse study reveals overlooked target for autism therapies
Blocking one form of an enzyme implicated in autism eases unusual behaviors and seizures in mice missing a top autism gene.
Blocking one form of an enzyme implicated in autism eases unusual behaviors and seizures in mice missing a top autism gene.
A new technique allows researchers to transplant human microglia into mouse brains and better study the association between these cells and autism.
An experimental drug tamps down the expression of a gene duplicated in an autism-related condition and restores typical behavior in mice.
Researchers have used a new gene-editing technique to delete a segment of DNA associated with autism and schizophrenia from mouse brain cells.
Female mice can withstand a maternal antibody that triggers brain abnormalities and autism-like behaviors in males. But additional immune challenges spell trouble.
Mice lacking one copy of a gene called DDX3X have developmental delay and sensory, motor and behavioral problems — similar to those seen in people with a mutation in the gene.
Delivery by cesarean section leads to subtle brain and behavioral alterations in mice, particularly those delivered prematurely.
Neurons in a brain region called the thalamus may regulate social behavior and play a key role in autism.
Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.
A method that visualizes nascent and migrating neurons in the mouse brain may shed light on brain development in autistic people.