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Spectrum: Autism Research News

Tag: mouse models

September 2020
Illustration of a neuron on top of a marijuana leaf surrounded by psychadelic colors.

Cannabis and autism, explained

by  /  7 September 2020

Autistic people and their families are increasingly experimenting with marijuana to try to ease problems such as insomnia, epilepsy and chronic pain — and traits of autism. But there is little evidence for its safety or effectiveness.

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Zebrafish embryos with various deformities.

CRISPR technique knocks down gene expression in animal embryos

by  /  2 September 2020

A new method that suppresses gene expression in the embryos of fish and mice may help researchers study autism genes in early development.

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August 2020
Two mice side-by-side.

Drug improves social behaviors, oxytocin signaling in autism mouse model

by  /  31 August 2020

Mice missing the autism gene NLGN3 have altered social behaviors and brain responses to the hormone oxytocin, both of which improve after treatment with a drug that helps regulate protein production.

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RNA, transcription

Antidote to ‘poison’ DNA may treat lethal form of epilepsy

by  /  26 August 2020

An experimental drug silences a DNA segment and seems to prevent seizures and death in a condition related to autism.

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Fat in bloodstream visualized as yellow balls, floating near blood cells, macro view.

Blood lipid levels may be altered in some autistic people

by  /  10 August 2020

About 6.5 percent of autistic people in the United States also have dyslipidemia, a condition characterized by abnormal lipids levels in the blood.

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July 2020
Person sleeping with EEG electrodes attached to head

Losing sleep: How researchers miss a key contributor to autism

by ,  /  16 July 2020

Doctors and scientists should consider sleep problems an integral part of autism and begin to study them in more rigorous ways.

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Mouse with optpgenetic device in its head

Wireless optogenetics device reveals new role for ‘cuddle hormone’

by  /  15 July 2020

A new wireless device switches oxytocin-producing neurons on and off in mice as they interact, showing the hormone’s effects depend on social context.

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Selective enzyme blocker eases fragile X traits in mice

by  /  10 July 2020

A new treatment prevents seizures and improves memory in a mouse model of fragile X syndrome, according to a new study.

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Fine-tuning brain activity reverses memory problems in mice with autism mutation

by  /  6 July 2020

Dampening overactive brain circuits alleviates social and memory problems in a mouse model of 22q11.2 deletion syndrome.

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June 2020

Study links gene to inherited form of autism

by  /  25 June 2020

Mutations in both copies of a gene called ACTL6B lead to autism, epilepsy and intellectual disability.

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