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Spectrum: Autism Research News

Tag: mouse models

October 2019
Two mice in a lab test environment

Single seizure may have long-lasting effects on brain

by  /  21 October 2019

A single seizure early in life leads to enduring behavioral problems, including diminished sociability, in mice.

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A new technique helps reveal patterns in the migration of neurons (green) to their destination (red).

A stop-motion movie of the whole brain, starring new neurons

by  /  21 October 2019

A method that visualizes nascent and migrating neurons in the mouse brain may shed light on brain development in autistic people.

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Two dark brown research mice

Mice with autism mutation reflect social difficulties seen in people

by  /  21 October 2019

A new autism mouse model carries the same mutation in a gene called ADNP that is seen in autistic people.

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Unusual gait marks mice with mutations related to autism

by  /  20 October 2019

Mouse models of two genetic conditions related to autism show abnormalities in their movement patterns.

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Transplanted neurons rescue social behavior but not brain circuits

by  /  20 October 2019

Injecting cells called interneurons into the brains of a mouse model of autism restores typical social behavior. But the reason for this effect is a puzzle.

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Grid of views of mouse brain: 3D and areas mapped in color

New mouse brain atlas merges two popular maps

by  /  20 October 2019

A new online resource aligns and improves the two most widely used mouse brain atlases.

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Skew in neuron numbers may explain sensory sensitivity in autism

by  /  20 October 2019

Loss of certain neurons on one side of the brain may explain why some autistic people are hypersensitive to touch.

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Signaling imbalance in mutant mice supports key autism theory

by  /  19 October 2019

Mice missing a copy of CHD8, a top autism gene, show a signaling imbalance in their brains — a finding in line with a popular hypothesis about autism’s origins.

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Study finds unexpected role for top autism gene

by  /  14 October 2019

SETD5, a leading candidate for autism risk, may control thousands of genes by modifying a protein involved in packaging DNA.

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Wireless device showers mouse brains with drugs, light

by  /  4 October 2019

A novel implant that delivers complex combinations of drugs and light to mouse brains may uncover the pathways that underlie repetitive behaviors in autistic people.

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