A new miniature iteration of a popular probe enables researchers to record activity at thousands of sites across the mouse brain and track the activity of individual neurons over months — providing long-term recording at an unprecedented scale.

An animated mouse reenacts common behavioral experiments and can be used to train algorithms that automatically track lab animals’ movements.

Many genes linked to autism, schizophrenia and neurodevelopmental delay regulate gene expression and support communication between neurons.

Deleting CHD8 from the intestines induces gastrointestinal and behavioral changes in mice that resemble traits in people with mutations in the gene.

A genetic therapy and an existing drug both restore typical brain size in mice missing DYRK1A, a top autism candidate gene, in the cerebral cortex, a new study shows. The animals typically have smaller brains than controls.

Anyone who uses multiple animals from a small number of litters to increase sample size is making a serious mistake. The similarities within individual litters will heavily skew the results.

Deleting the autism-linked gene CHD8 from specific cells in the cerebellum, a brain region important for movement, leads to motor deficits but does not alter social behaviors in mice.

Autistic children are up to four times as likely as their non-autistic peers to have digestive problems, and several small studies show they may also have atypical microbial communities living in their guts.

Mutations in CUL3, a gene strongly linked to autism, may cause differences in brain structure by disrupting cytoskeleton proteins, according to a new study.

Too little — or too much — of certain substances during pregnancy may increase the odds of having a child with autism. Here we explain what scientists know about these associations.