Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.

Mice with a mutation in their mitochondrial DNA show altered brain activity, repetitive behaviors and reduced sociability, according to a new study.

A new tool enables researchers to create mosaic mutations in only some cells and then accurately identify which cells are affected.

A glowing protein tracks serotonin levels and location in the brains of living mice and could yield clues to the neurotransmitter’s role in autism.

A Hollywood-inspired video tool that captures movement in three dimensions over extended time periods shows that rats lacking the autism-linked gene FMR1 have different grooming patterns than controls do.

On 10 February, André Fenton spoke about rethinking dysfunction in fragile X model mice.

Mice missing a copy of MAGEL2 have trouble discerning between a familiar mouse and an unfamiliar one; treating them with the social hormone vasopressin reverses this deficit.

Mutations in the autism-linked gene DNMT3A lead to the behaviors and gene-expression changes seen in different neurodevelopmental conditions.

Sensory problems in people with fragile X syndrome may stem from hyperactive neurons, a mouse model study suggests.

Female mice missing a copy of the autism-linked gene MECP2 in a specific set of inhibitory neurons have a hard time heeding pups’ calls and herding litters.