Chandelier cells may sprout few branches in autism brains
Specialized neurons called chandelier cells, which dampen brain signals, make unusually few connections in the brains of people with autism.
Specialized neurons called chandelier cells, which dampen brain signals, make unusually few connections in the brains of people with autism.
Experiences may shape the human brain by altering neurons that boost brain activity.
Mice lacking one copy of a leading autism gene have hyperexcitable brains and problems with learning and memory.
An unprecedented look at gene expression in tens of thousands of brain cells from autistic people suggests important roles in the condition for a neuronal subtype and for microglia.
In mice exposed to maternal inflammation in the womb, a key chemical messenger never makes the switch from exciting brain signals to inhibiting them.
New results from brain scans of adults with autism are at odds with the popular theory that the condition involves weak brakes on brain activity.
Autism parents fall for the marketing of essential oils, the pruning hypothesis of brain development matures, and an online manual classifies mouse behavior.
Researchers have repurposed the gene-editing tool CRISPR to dial down a gene’s activity in select subtypes of neurons in mice.
A fusion of two existing drugs alleviates autism-like features in a mouse model of the condition.
A widely used treatment for anxiety can eliminate some of the cognitive and social problems seen in mice missing a copy of ARID1B, a gene associated with autism.