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Tag: inhibitory signaling

August 2015
News

Mathematical model of autism bridges brain, behavior

by  /  13 August 2015

A mathematical model of the brain’s circuits shows how neurons stuck in overdrive could produce symptoms of autism. The model may reveal how autism-linked behaviors arise from underlying biology.

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July 2015
News

From tiny slice, researchers lay bare beauty of mouse brain

by  /  30 July 2015

Researchers have reconstructed in spectacular detail all of the complex circuits in a small piece of the mouse brain. They revealed the sublime images today in Cell.

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News

Lab-spun spheres reveal common biology in boys with autism

by  /  16 July 2015

Balls of neurons derived from skin cells of four boys with autism show shared alterations in biology and gene expression, researchers reported today in Cell. The findings finger FOXG1, a gene involved in brain development, as a player in autism.

2 Comments
June 2015
Multimedia / Webinars

William Catterall examines anxiety drugs for autism

24 June 2015

Watch the complete replay of William Catterall explaining how low doses of an anxiety drug alleviate autism-like symptoms in mice.

5 Comments
April 2015
Opinion

Mouse studies support second chance for fragile X drug

by  /  28 April 2015

Two new studies give a boost to arbaclofen, which failed to meet expectations in clinical trials for autism and fragile X syndrome.

6 Comments
News

Brain connections give clues to sensory problems in autism

by  /  23 April 2015

Signals that relay sensations from nerves to the brain are abnormally strong in people with autism, a finding that may explain why some people with the disorder are overly sensitive to light, sound and touch.

5 Comments
Opinion

Blood pressure drug may protect brain from seizures

by  /  7 April 2015

A blood pressure drug called bumetanide may shield the brain from the effects of severe seizures early in life.

10 Comments
February 2015
News / Toolbox

Flexible implant gently eavesdrops on brain signals

by  /  11 February 2015

An ultra-thin and flexible electrode array can record brain signals without disturbing the underlying tissue.

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January 2015
News

Surplus of neurons spurs autism traits in mice

by  /  15 January 2015

Fetal mice that have too many neurons grow to show social deficits and repetitive behaviors. The finding, reported 11 December in Cell Reports, debuts a mouse model of autism that’s based on a biological abnormality seen in some people with the disorder.

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November 2014
News

Autism-linked gene guides growth of subtype of neurons

by  /  19 November 2014

Mice missing PTEN, a strong autism candidate gene, in a subtype of inhibitory neurons in one part of the brain show signaling abnormalities and social deficits. Researchers presented the unpublished work yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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