The expression levels of certain genes that track with brain activity are different in autistic people than in their non-autistic peers.
Spectrum: Autism Research News
Tag: gene expression
Long cast in supporting roles in the brain, astrocytes are now emerging as primary players in certain characteristics of autism and related conditions.
The vast stretches of DNA that don’t code for proteins could fill key knowledge gaps about autism genetics. But making sense of it all won’t be easy.
The catalog could help researchers understand the effects of autism-linked DNA variants that fall outside genes.
Genetic factors could help explain why the ‘social hormone’ failed to benefit autistic people in a phase 3 clinical trial last year.
Swiss biotech Stalicla hopes to bring precision medicine to autism. Experts praise efforts to identify autism subgroups, but evidence to support the company’s claims has yet to be seen.
Neurons with a faulty copy of SETD1A, a gene tied to autism and schizophrenia, show structural abnormalities and altered connectivity patterns.
Scientists have at last filled in the missing gaps — an advance likely to inform every aspect of autism genetics research, Eichler says.
The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.
Together, the neurons are part of the corticostriatal circuit, which has been implicated in autism.