What studying worms, flies and fish says about autism
Researchers are increasingly turning to simple animals to learn about autism biology and find leads for new drugs.
Researchers are increasingly turning to simple animals to learn about autism biology and find leads for new drugs.
Mice exposed to unusually low levels of the placental hormone allopregnanolone in the womb show atypical brain development and autism-like behaviors.
Brain cells from the cerebellums of mice that model tuberous sclerosis show dampened levels of proteins controlled by FMRP, the protein missing in fragile X syndrome.
Spontaneous mutations in parts of the genome that regulate gene EBF3 appear to contribute to autism risk.
The software compares gene expression in cells derived from organoids with a reference atlas of the developing mouse brain.
Many of the genes strongly linked to autism are involved in the remodeling of chromatin, the complex of DNA and proteins that makes up chromosomes. Scientists are just beginning to understand why.
A new spin on the classic CRISPR gene-editing tool can alter the genome’s chemical tags and suppress gene expression for months.
Atypical patterns of neuronal activity and gene expression in the striatum may characterize autism in girls, according to a new study.
About one-third of the HNRNP gene family’s 33 members may be associated with neurodevelopmental conditions, including autism.
Deleting CHD8 from the intestines induces gastrointestinal and behavioral changes in mice that resemble traits in people with mutations in the gene.