Tag: gene expression

May 2020
News

Extra proteins alter microglia and behavior in mice

by  /  29 May 2020

The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.

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Human brain with prefrontal cortex highlighted.
News

DNA differences may shape gene expression in the brain before birth

by  /  7 May 2020

Many genes in a brain region implicated in autism change expression patterns in late fetal development, depending on differences in neighboring DNA.

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April 2020
News / Toolbox

New atlas maps gene expression throughout the brain

by  /  22 April 2020

A comprehensive atlas of gene expression by brain region could spur new research on autism.

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March 2020
Coloured transmission electron micrograph (TEM) showing several unmyelinated (green) and myelinated (green with blue border) axons. Schwann cell cytoplasm is red and a nucleus (bottom left) is yellow. The pink lines are the basement membranes.
News

Loss of insulation on neurons may contribute to autism

by  /  6 March 2020

Genes involved in the formation of myelin, a fatty substance that sheathes neurons, are altered in autistic people and in several mouse models.

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February 2020
Toddler is balancing with help from mom
News

Little-known gene tied to autism, developmental delay

by  /  28 February 2020

Rare mutations in a gene called BAZ2B are associated with various conditions of brain development, including autism.

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January 2020
Micrograph of brain organoid in green and red
News

Spheres of brain cells may offer crystal ball for autism’s origins

by  /  24 January 2020

Researchers have monitored the active genome in brain organoids over the course of nearly two years — and may find clues to autism’s roots.

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News

Autism’s genetic drivers may differ by sex

by  /  9 January 2020

Autism may stem from a different — and larger — set of genetic mutations in women than it does in men.

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December 2019
Features / Special Reports / 2019: Year in review

Notable papers in autism research in 2019

23 December 2019

This year’s top papers deepen our understanding of autism’s genetics and reveal mixed results from trials of autism therapies.

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Mice neurons seen in green
News

Loss of autism gene may lead to pile-up of proteins in neurons

by  /  19 December 2019

A shortage of CUL3, a leading autism gene, may impair social behavior in mice by ramping up protein production in neurons.

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November 2019
News / Toolbox

High-frequency sound waves locate cells in deep tissues

by  /  22 November 2019

A new technique uses ultrasound instead of light to detect gene expression in cells.

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