Autism-linked genes clock daily oscillations
Rhythmic variations in the genes’ brain expression levels may help explain the sleep problems that often accompany the condition.
Rhythmic variations in the genes’ brain expression levels may help explain the sleep problems that often accompany the condition.
Data from two separate research teams suggest the cells are key to sensory hypersensitivity in fragile X syndrome.
An analysis of 11 cortical regions shows anterior-to-posterior shifts in gene expression linked to autism.
The developmental models have advantages over natural embryos and other synthetic models, such as organoids, but present technical and ethical challenges.
A meeting in Texas reckons with the future of treatment, following two setbacks in 2020.
The transplanted cells integrate into living animals’ neural circuitry and influence behavior.
The prize recognizes Geschwind’s contributions to our understanding of autism genetics.
A 341-repeat mutation from a person with fragile X does not lead to the syndrome’s traits or function the same way in mice, highlighting a need for different animal models.
The new tool may help researchers reconstruct the sequence of biological events that underlie development.
Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.