The developmental models have advantages over natural embryos and other synthetic models, such as organoids, but present technical and ethical challenges.

A meeting in Texas reckons with the future of treatment, following two setbacks in 2020.

The transplanted cells integrate into living animals’ neural circuitry and influence behavior.

The prize recognizes Geschwind’s contributions to our understanding of autism genetics.

A 341-repeat mutation from a person with fragile X does not lead to the syndrome’s traits or function the same way in mice, highlighting a need for different animal models.

The new tool may help researchers reconstruct the sequence of biological events that underlie development.

Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.

The mutations occur spontaneously in noncoding stretches of DNA that control gene expression.

An overabundance of ribosomes drives an imbalance of proteins produced from long and short genetic transcripts in a mouse model of fragile X syndrome.

Deletion of the 22q11.2 chromosomal region alters the expression of numerous autism- and schizophrenia-linked genes, most of which are not contained within the deleted region, a new study suggests.