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International Society for Autism Research 2021 Virtual

INSAR 2021
Chart compiling the deletions and duplications linked to various neurodevelopmental traits.

Massive analysis scores genes’ sensitivity to mutations

by  /  5 May 2021
Researchers have rated more than 17,000 genes, including many linked to autism and other neuropsychiatric conditions, according to their sensitivity to deletions and duplications.
INSAR 2021
Computer screen reflection in spectacles of DNA profile, close up of face

New ranking system flags clinically relevant ‘autism genes’

by  /  5 May 2021
A novel method to evaluate the strength of the evidence linking autism to specific genes could reveal which ones are most useful to screen for.
INSAR 2021
Mouse gut cells in blue, purple and pink

Loss of top autism-linked gene from gut alters behavior in mice

by  /  4 May 2021
Deleting CHD8 from the intestines induces gastrointestinal and behavioral changes in mice that resemble traits in people with mutations in the gene.
May 2021
Woman is holding her fingers to her forehead in pain.
INSAR 2021

Pain keeps autistic women and girls home from work, school

by  /  4 May 2021

More autistic women and girls report daily pain than do men and boys with the condition.

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Younger brother giving older brother a haircut at home.
INSAR 2021

Siblings boost autistic people’s daily-living skills

by  /  4 May 2021

Autistic people with at least one sibling make greater gains in adaptive functioning than their only-child counterparts do.

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INSAR 2021

Anxiety specific to autism linked to amygdala differences

by  /  3 May 2021

People who experience an autism-specific form of anxiety also tend to have an unusually small amygdala, a brain region associated with emotion processing and fear, according to a new unpublished study.

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young woman sitting on steps alone, looking anxious.
INSAR 2021

Anxiety, self-harm elevated in people with DDX3X syndrome

by  /  3 May 2021

Girls and women with mutations in the autism-linked gene DDX3X may be particularly vulnerable to anxiety and self-harm.

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brainstem of rats in red, green and blue highlight higher levels of GABA.
INSAR 2021

GABA agonist rescues auditory hypersensitivity in rats missing autism-linked gene CNTNAP2

by  /  3 May 2021

The investigational drug arbaclofen may right an imbalance between inhibitory and excitatory signaling in the animals’ brains.

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