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Spectrum: Autism Research News

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The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

December 2010

Molecular mechanisms: Lithium treats adult fragile X symptoms

by  /  8 December 2010

Treating adult mice with lithium restores the ability of neurons in fragile X mice to fine-tune their signaling, according to a study published online in November in Brain Research.

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Molecular mechanisms: Autism brains have altered neurons

by  /  7 December 2010

Changes in the bodies of neurons may account for communication deficits in the brains of people with autism, according to a study published 3 November in The Journal of Neuroscience.

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Flow of water in the brain fingers autism

by  /  6 December 2010

An analysis of brain scans correctly distinguishes between people with autism and controls more than 90 percent of the time, according to a study published today in Autism Research.

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Stimulating research

by  /  6 December 2010

The National Database for Autism Research (NDAR), created by the National Institutes of Health to ease data sharing among autism researchers, has released the first batch of data on more than 10,000 participants enrolled in federally funded autism research studies.

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Molecular mechanisms: New pathway for fragile X treatment

by  /  2 December 2010

Inhibiting the ERK1/2 pathway — which regulates the synthesis of other proteins — can rescue some of the effects of fragile X syndrome, according to a study published 17 November in the Journal of Neuroscience. The ERK pathway could provide a novel target for fragile X therapies.

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Risk gene for autism rewires the brain

by  /  1 December 2010

A variant of the autism risk gene CNTNAP2 may alter the brain to emphasize connections between nearby regions and diminish those between more distant ones, according to a study published 3 November in Science Translational Medicine.

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Cognition and behavior: Brain maps direct our attention

by  /  1 December 2010

The parts of the brain that help us pay attention to some things and not others have specialized regions for different senses, such as sight and sound, according to a paper published online in November in the Proceedings of the National Academy of Sciences.

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November 2010

Molecular mechanisms: Researchers light up interactions between neurons

by  /  30 November 2010

Researchers have developed a technique to detect interactions in live neurons between neuroligins and neurexins — two proteins known to bind at the junction between neurons, according to a study published 29 October in Cell.

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Mapping the mind

by  /  26 November 2010

Chinese researchers have developed a new imaging system, called micro-optical sectioning tomography or MOST, to generate a three-dimensional image of neurons in a whole mouse brain.

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‘Daydreaming’ circuit implicated in autism, attention deficit

by  /  24 November 2010

Areas of the brain that are active when people are daydreaming or sleeping, and quiet when they are engaged in a task, are imperfectly synchronized in people with autism and attention deficit hyperactivity disorder, researchers say.

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