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Spectrum: Autism Research News

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The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

January 2011

Some siblings of children with autism only share traits

by  /  10 January 2011

The goal of studying siblings of children with autism is to identify an early diagnostic marker for the disorder. What researchers are finding instead are distinct traits shared by family members who remain healthy.

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Cognition and behavior: Children with autism heed irrelevant images

by  /  5 January 2011

Children with autism are less interested in watching an activity, such as a parent and child putting together a puzzle, compared with typically developing controls, according to a study published in November in Brain Research.

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High-tech national project set to trace brain’s connections

by  /  4 January 2011

Over the next five years, dozens of researchers funded by the $40 million ‘NIH Human Connectome Project’ will map the circuits of the human brain, tracing neural pathways and learning how different regions work together in synchrony.

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December 2010

The culture of gender

by  /  29 December 2010

Delusions of Gender takes issue with sexism disguised as scientific fact. I think the book is a provocative cautionary tale for autism researchers.

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Jumping genes implicated in Rett syndrome

by  /  27 December 2010

The neurons of people with Rett syndrome contain an overabundance of retrotransposons — DNA sequences that copy and insert themselves into new spots throughout the genome — during early development, according to a study published 18 November in Nature.

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Scientists capture microglia’s role in brain connectivity

by  /  20 December 2010

Scientists are changing their minds about the role of microglia, the brain’s strongest and most agile soldiers against damage and infection. In healthy brains, microglia help build and eliminate synapses, the junctions between neurons, according to a study published 2 November in PLoS Biology.

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Molecular mechanisms: Imaging technique reveals brain’s diversity

by  /  14 December 2010

A new technique called array tomography allows researchers to visualize individual synapses, the complex junctions between neurons, in the mouse brain. Researchers have also identified several markers that highlight the incredible diversity of synapse types.

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The full spectrum

by  /  14 December 2010

Scientists have debated the relationship between autism and schizophrenia for decades. A review published last month suggests they are two sides of the same neurobiological coin.

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Scientists create mouse models of chromosome 16 defects

by  /  13 December 2010

Two independent groups have created mice that have deletions or duplications in a large section of chromosome 16. Each team has produced an animal with a different set of features, some of which — such as large head size and repetitive behaviors — are reminiscent of people with autism.

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Calming neurons may ease apnea in Rett syndrome

by  /  9 December 2010

A controversial new approach that quiets the activity of certain neurons in the brain alleviates breathing difficulties in a mouse model of Rett syndrome, according to a study published 4 October in the Proceedings of the National Academy of Sciences.

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