A new viral variant can deliver genes exclusively to the brain, overcoming a key hurdle in treating neurological conditions using gene therapy.
Spectrum: Autism Research News
Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.
Loss of the POGZ gene in mice makes certain genes inaccessible and prevents their expression.
Oxytocin, cemented in the popular imagination as the “love molecule,” could serve as a treatment for some autistic people who naturally have low levels of the hormone, researchers say.
Mice that express a fluorescent synaptic receptor reveal the interactions between neurons in unprecedented detail.
The investigational drug arbaclofen makes autistic people’s brains respond to a visual task more like non-autistic people’s brains do.
As 2021 comes to a close, Spectrum recaps some of the biggest trends in autism science this year: studies of sex differences, noncoding regions of the genome and points of convergence, as well as efforts to improve screening and participatory research.
Developmental delay, intellectual disability and behavioral issues are common among people who have mutations in MYT1L, a gene with strong ties to autism.
New software can automatically identify and quantify mouse social behavior from videos, saving researchers time.
Mice missing a copy of the gene SENP1 have atypical social behavior likely due to a signaling imbalance in the retrosplenial cortex.