TOPIC

The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

News / Toolbox
Mouse hippocampus view

New method yields maps of gene expression in multiple dimensions

by  /  24 May 2019
An array of minute beads enables researchers to build precise maps of gene expression in the brain.
News
Neurons firing and lighting up

Single-cell analysis suggests brain signaling problems in autism

by ,  /  22 May 2019
Recent advances in technology allow researchers to measure RNA that is contained within the nucleus of a single brain cell.
News / Toolbox
grid of lab grown neurons

New method creates uniform cultures of lab-grown neurons

by  /  16 May 2019
A new technique leads to neuron cultures of consistent quality, enabling scientists to study how autism mutations alter neurons.
May 2019
Man and woman portraits on a "family tree"
Features / Deep Dive

What the ‘broad spectrum’ can teach us about autism

by  /  15 May 2019

The relatives of autistic people often have mild traits of the condition. Studying these family members could broaden our understanding of autism.

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organoid
News / Toolbox

New method creates complex, long-lived brain ‘organoids’

by  /  10 May 2019

A new method for growing brain organoids allows them to survive for up to a year — more than four times as long as is possible with other methods.

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neurons in mice brains
News

Inflammation may wield sex-specific effects on developing brain

by  /  8 May 2019

Exposure to inflammation in the womb may affect the brain and behavior of males and females differently.

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Child in magnetoencephalograph (MEG) scanner
News

Brains of minimally verbal autistic children respond slowly to sound

by  /  4 May 2019

Several of the brain’s responses to sound are sluggish in autistic children who speak few or no words, compared with those who are verbal.

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Image of DNA made up of hundreds of tiny images in a mosaic effect.
News / Toolbox

New algorithm identifies rare mutations in single neurons

by  /  3 May 2019

A new computational method sifts true mutations from spurious ones in a single cell’s genome.

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News

Severe heart conditions may increase odds of autism

by  /  3 May 2019

Autism is more common among children who have undergone open heart surgery for a congenital heart condition than it is in the general population.

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Nasal spray jetting from bottle on a dark background
News

Ready or not, two drugs for autism edge closer to clinic

by  /  1 May 2019

Two drugs that alter the activity of the hormone vasopressin seem to improve social communication in autistic people, but some experts question the findings.

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News

The signaling imbalance theory of autism, explained

by  /  1 May 2019

The signaling imbalance theory holds that the brains of autistic people are hyper-excitable because of either excess neuronal activity or weak brakes on that activity.

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Illustration shows the world is distorted through a point of view pair of glasses
News

The predictive coding theory of autism, explained

by  /  1 May 2019

In autism, a person’s brain may not form accurate predictions of imminent experiences, or even if it does, sensory input may override those predictions.

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overlapping network of connections in the brain
News

The connectivity theory of autism, explained

by  /  1 May 2019

A growing body of evidence suggests that autism involves atypical communication between brain regions, but how and where in the brain this plays out is unclear.

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