TOPIC

The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

News

Young children with autism may show brain-fluid buildup

by  /  19 November 2018
Autistic children aged 2 to 4 have about 15 percent more fluid between their skull and their brain than their typical peers do.
News / Toolbox

Mouse brain atlas reveals details of developing cerebellum

by  /  16 November 2018
A new database displays gene-expression patterns in individual cells of the developing mouse cerebellum over time.
News

Top autism gene may rewire brain by altering expression of other genes

by  /  15 November 2018
The autism gene TBR1 controls the expression of several other candidate genes that govern the architecture of the brain's outer section.
November 2018
Purkinje neurons glow red in this section.
News

Cerebellum’s role in autism may depend on timing

by  /  12 November 2018

Two studies published in the past two months provide new clues to when and how the cerebellum contributes to autism.

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News

Neuron tag may shield synapses from brain’s pruning shears

by  /  12 November 2018

A protective molecular tag on neurons can prevent microglia, the brain’s immune cells, from trimming away their connections with other neurons.

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Delicate network of neurons and synapses.
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Webbing around neurons altered in autism mouse models

by  /  8 November 2018

Lattice-like structures that surround neurons may be overly abundant — or scarce — in brain regions of three autism mouse models.

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Two hands hold two pills, one red and one blue.
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Drug duo delivers brain, behavioral benefits for fragile X syndrome

by  /  8 November 2018

Administering a cholesterol drug alongside an antibiotic eases atypical behavior and restores the signaling balance in the brains of people with fragile X syndrome.

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Toddle boy having his head measured in a medical setting.
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Brain organoid study firmly links autism mutations to RhoA

by  /  7 November 2018

A cellular pathway that helps neurons grow and move during fetal development may drive the changes in head size in some autistic people.

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Infant in fnirs cap, wrapped in blankets.
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Study tracks social brain development in African infants

by  /  7 November 2018

An inexpensive, noninvasive method can track social brain development in infants in low-resource countries.

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Artistic interpretation of a neuron in the hippocampus.
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Subset of neurons may underlie brain’s response to experience

by  /  7 November 2018

Experiences may shape the human brain by altering neurons that boost brain activity.

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Two white mice, one on a wheel, sniff noses.
News

Infection during childhood may aggravate autism risk from mutation

by  /  7 November 2018

Triggering an immune defense in newborn male mice missing a copy of TSC2, a gene linked to autism, impairs the mice’s social memory.

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News

Study links changes in blood flow to autism

by  /  7 November 2018

Mice with an autism-linked deletion in chromosome 16 show abnormalities in their blood vessels and circulation.

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Chandelier cells send their signals through fibers arranged in vertical columns that are reminiscent of the candles in a chandelier.
News

Chandelier cells may sprout few branches in autism brains

by  /  7 November 2018

Specialized neurons called chandelier cells, which dampen brain signals, make unusually few connections in the brains of people with autism.

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