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The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

News
white mouse on a green activity wheel

Patterns in heart rate, pupil size may predict Rett syndrome

by  /  18 September 2019
Heart-rate patterns and changes in pupil size may herald Rett syndrome, autism or related conditions.
News
Woman inside MRI machine with clinicians or doctors looking on with clipboards

Autistic girls’ brains show distinct anatomical features

by  /  16 September 2019
Nerve fiber tracts in the brains of autistic girls appear more fragmented than those of typical girls’. Autistic boys’ brains, meanwhile, look like those of typical boys.
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Glowing neurons in the transparent young zebrafish highlight activity in its brain and muscles.

Zebrafish show true colors as models for autism sleep studies

by  /  13 September 2019
Sleeping zebrafish show two patterns of neuronal activity that are analogous to those in people.
September 2019
triangle effect digital rendering shows the shapes of a red neuron network
News

Drug screen reveals potential treatments for Rett syndrome

by  /  11 September 2019

An experimental leukemia drug and a chemical in black pepper ease breathing and movement problems in a mouse model of Rett syndrome.

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News

Protein ‘bubbles’ released from neurons may play role in autism

by  /  4 September 2019

Problems with protein-filled parcels called exosomes may contribute to Rett syndrome, a condition related to autism.

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August 2019
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New maps of neuronal connections reveal roundworms’ wiring

by  /  30 August 2019

Two new maps show the entire nervous system of the adult roundworm Caenorhabditis elegans.

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News

Brain organoids show realistic neuronal firing rhythms

by  /  29 August 2019

Brain organoids made from typical human stem cells begin to show synchronized neuronal firing patterns after growing in a dish for at least four months.

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News

Mice reveal how top autism gene may disrupt brain structure

by  /  26 August 2019

Mutations in an autism gene called ANK2 may alter brain wiring by causing the growth of excess neuronal connections.

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graphic shows eye movement patterns
News

Visual task may offer brain marker for autism

by  /  19 August 2019

People with autism may show an altered pattern of brain activity when looking at two competing images.

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News

Levels of brain chemicals may reflect severity of autism traits

by  /  19 August 2019

The levels of four chemicals in the brain may distinguish autism and vary with its severity, according to a new study.

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Mouse squeaks may be poor analog for human speech

by  /  16 August 2019

The brain areas involved in mice’s ultrasonic vocalizations may not be the same as those that govern human speech.

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News

What matters for protein linked to autism? Location, location, location

by  /  14 August 2019

One form of the protein implicated in Angelman syndrome and autism clusters in the nucleus, and it’s this form that may be critical to brain development.

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Portrait of scientist Alysson Muotri
News / Profiles

Autism researcher Alysson Muotri’s audacious plans for brain organoids

by  /  12 August 2019

Alysson Muotri aims to build a ‘thinking’ brain as a model for autism — even if his colleagues consider that work controversial.

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