A new computational approach predicts how sequence variations in both the coding and noncoding regions of a gene affect the gene’s expression. The method, described today in Science, may help researchers understand how specific variants contribute to disorders such as autism.

Researchers have for the first time isolated and characterized protein complexes found at the points of connection between neurons. Mutations in some of these proteins are linked to autism.

A new method called iDISCO makes tissue more transparent and permeable to antibodies, allowing researchers a deeper view into the brain and other organs.

A new study points to a possible link between inflammation in the womb, brain overgrowth and the behavioral impairments seen in autism.
 

A rare form of autism linked to a duplication of the 15q11-13 chromosomal region shares a molecular signature with more common forms of the disorder, suggests unpublished research presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

The expression patterns of microRNAs vary less by brain region and age in people with autism than in controls. Researchers presented the unpublished findings Tuesday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

Infection with group B streptococcus bacteria in pregnant rats triggers brain abnormalities and autism-like behaviors in their pups — especially in males. Researchers presented the unpublished results today at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

A new online database called Braineac details how variations in DNA sequence shape gene expression in the human brain.

Having an enlarged head in early childhood is not a reliable marker of autism, according to two new studies that tracked changes in head and body size in children over time.

Watch the complete replay of David Amaral and Alison Singer’s webinar on the potential of postmortem brain research for understanding autism.