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Spectrum: Autism Research News

Tag: postmortem brains

September 2015

Sweet formula seamlessly crafts see-through brains

by  /  30 September 2015

Using a sugar alcohol found in fruit, researchers have concocted a new chemical cocktail for making brains transparent.

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August 2015
Week of AugustAug
10th
2015

Spotted: Building brains; classification controversy

by  /  14 August 2015

A 3D printer makes brains out of bio-ink, and researchers debate the number of types of neurons.

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March 2015

Women with severe autism point to new gene candidates

by  /  26 March 2015

Looking in families with a history of severe autism among women, researchers have unearthed 18 new candidate genes for the disorder. One of these genes, delta-catenin, plays a critical role in brain development, researchers reported yesterday in Nature.

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Studies trace far-reaching effects of single autism gene

by  /  19 March 2015

Scientists peel back the layers of genetic complexity in autism, starting with the master regulator CHD8.
 

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February 2015

Timed cues create mini-cerebellum in culture

by  /  25 February 2015

Researchers can coax human stem cells to grow into layered structures that mimic the brain’s center for motor control, the cerebellum.

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January 2015

Small snippets of genes may have big effects in autism

by  /  22 January 2015

Small pieces of DNA within genes, dubbed ‘microexons,’ are abnormally regulated in people with autism, suggests a study of postmortem brains.

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Method charts lifetime expression of DNA in brain

by  /  21 January 2015

A new database that maps changes in gene expression in the prefrontal cortex shows that autism-linked genes are expressed differently than other genes through six stages of life.

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Surplus of neurons spurs autism traits in mice

by  /  15 January 2015

Fetal mice that have too many neurons grow to show social deficits and repetitive behaviors. The finding, reported 11 December in Cell Reports, debuts a mouse model of autism that’s based on a biological abnormality seen in some people with the disorder.

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December 2014

Notable papers of 2014

by  /  22 December 2014

It’s no easy feat to whittle down the list of the most influential autism papers to a mere 10. So please consider this but a taste of the burgeoning field, presented in chronological order and based on suggestions from many researchers.

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Postmortem brains point to molecular signature of autism

by  /  22 December 2014

An analysis of genes expressed in the postmortem brains of people with autism has identified three molecular pathways linked to the disorder. The findings, published 10 December in Nature Communications, add to mounting evidence that the myriad causes of autism converge on common biological processes.

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