A minority of boys with autism have brains that are unusually large relative to their bodies — a trait tied to regression and intellectual disability.

Some neurons preferentially express the copy of a gene inherited from one parent over the other.

The brains of people with autism show a distinct molecular signature that reflects alterations in how genes are pieced together and expressed.

The brains of many people with autism may exhibit a characteristic arrangement of chemical groups on the proteins that DNA coils around.

Our picks for the top 10 papers of the year highlight leaps in our understanding of autism, as well as lingering gaps.

A new chart of DNA’s three-dimensional structure reveals genomic regions that control distant genes during development.

Gene expression in so-called ‘organoids’ resembles the pattern seen in the first few weeks of a developing brain.

A massive collection of brain tissue reveals common genetic variants that influence gene expression in the brain.

A university must pay the U.S. government $9.5 billion for false claims on federal grants, a mother explains her decision to donate her son’s brain to science, and investigators struggle to enroll families in autism research.

A potent chemical cocktail renders tissue transparent in a way that makes even buried brain structures visible.