Atypical development of a particular type of neuron explains the structural similarities seen in the brains of people with autism, schizophrenia and other conditions, according to a new study.
A new study pinpoints the genes and cell types that may underlie the atypical brain structure seen in people with genetic conditions linked to autism.
Nearly all genes with moderate to strong ties to autism are expressed in the developing amygdala; a few show altered expression in the amygdalae of autistic people.
The amygdala has long been a focus of autism research. But its exact role in the condition has been unclear.
Many genes in a brain region implicated in autism change expression patterns in late fetal development, depending on differences in neighboring DNA.
Rare mutations in a gene called BAZ2B are associated with various conditions of brain development, including autism.
This year’s top papers deepen our understanding of autism’s genetics and reveal mixed results from trials of autism therapies.
Blood vessels in the brains of more than half of autistic people have an unusually large number of T cells.
We asked five autism researchers to weigh in on whether there is a unique brain signature for autism and, if so, how to identify it.
A set of neurons involved in complex cognitive functions may play a central role in autism.