Atlas of gene activity in prenatal brain holds clues to autism
Genes exert their strongest influence on the brain in the first half of gestation — a key window for autism and other neurodevelopmental conditions.
Genes exert their strongest influence on the brain in the first half of gestation — a key window for autism and other neurodevelopmental conditions.
Postmortem brain samples from people with one of six conditions, including autism, show distinct signatures of over- and underexpression of immune genes.
Such high expression levels may account for the condition’s sex bias, a new preprint suggests — but not everyone agrees with that logic.
The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.
People with dup15q syndrome and those with idiopathic autism have similar patterns of altered gene expression in early brain development and later in life.
The prize recognizes Geschwind’s contributions to our understanding of autism genetics.
Long cast in supporting roles in the brain, astrocytes are now emerging as primary players in certain characteristics of autism and related conditions.
Having a genetic predisposition to inflammation is linked to structural changes in brain regions implicated in neurodevelopmental conditions.
The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.
The fact that autism seems to affect more boys than girls is often attributed to diagnostic gaps, but the skew remains largely unexplained. Some scientists are turning to basic biology for answers.