Having a genetic predisposition to inflammation is linked to structural changes in brain regions implicated in neurodevelopmental conditions.
Spectrum: Autism Research News
Tag: postmortem brains
The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.
The fact that autism seems to affect more boys than girls is often attributed to diagnostic gaps, but the skew remains largely unexplained. Some scientists are turning to basic biology for answers.
The work fills in gaps about how synapses change before and after birth — essential knowledge for understanding whether synapse development differs in autism.
The postmortem brain tissue available for autism research is overwhelmingly from people of Western European heritage. Verónica Martínez-Cerdeño and her colleagues are working to change that.
Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.
A new study pinpoints the genes and cell types that may underlie the atypical brain structure seen in people with genetic conditions linked to autism.
An analysis of four molecular datasets shows a distinct signature, including changes in gene expression and chemical DNA modifications, in some autism brains.