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Tag: SHANK3

April 2018
four scientists standing on colorful tile
News

CRISPR goes wild, and scientists debate its fidelity

by  /  30 April 2018

The gene-editing tool CRISPR may cause thousands of off-target mutations, but critics say it’s way too soon to accuse it of infidelity.

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A cancer drug boosts levels of a key protein (red) in mice lacking SHANK3.
News

Cancer drug shows promise for treating some forms of autism

by  /  2 April 2018

A low dose of a drug used to treat lymphoma may ease social problems in some forms of autism.

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March 2018
Opinion / Viewpoint

Explaining ‘resilience’ in autism may seed new therapies

by  /  27 March 2018

Some individuals who have autism mutations show no signs of the condition; understanding why may lead to treatments.

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Mouse in a lab or maze hops around sniffing here and there
Features / Deep Dive

Why studying autism in mice may be doomed to fail

by  /  21 March 2018

After more than a decade of effort, scientists are questioning whether mouse models of autism can ever capture the social deficits seen in people with the condition.

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January 2018
Week of JanuaryJan
22nd
2018
News / Spotted

Pollutant surprise; monkey clones; researchers rattled and more

by  /  26 January 2018

Researchers find a surprising link between certain pollutants and reduced autism risk, the world welcomes — and fears — the first primate clones, and new U.S. clinical trial rules reverberate globally.

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November 2017
Movement maps of children with Phelan-McDermid syndrome
News

Drug improves gait in children with Phelan-McDermid syndrome

by  /  12 November 2017

A new measure of motor skills suggests that insulin-like growth factor 1 improves movement in people with Phelan-McDermid syndrome.

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large adult hands holding small children's hands
News

Soothing sensory sensitivity may ease social problems in mice

by  /  12 November 2017

A treatment delivered to neurons that mediate touch can ease anxiety and social problems in two mouse models of autism.

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Zebrafish form large groups, called shoals,
News

SHANK3 zebrafish may be too cool for schools

by  /  12 November 2017

Zebrafish lacking the autism-linked gene SHANK3 show little social interest and other behavioral abnormalities.

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October 2017
Julio Resto, lead caretaker on Cayo Santiago, dumps a bag of monkey chow. The storm leveled feeding corrals on the island.
News

Researchers rally to save monkeys on hurricane-ravaged island

by  /  5 October 2017

Hurricane Maria pummeled Cayo Santiago, home to more than 1,500 rhesus macaques, including some used for autism research.

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September 2017
Macaque monkey in the wild
News

Monkey model reveals new role for top autism gene

by  /  11 September 2017

Monkeys missing the gene SHANK3 have too few neurons in the prefrontal cortex, a brain region involved in planning and social behavior.

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