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Spectrum: Autism Research News

Tag: SHANK3

February 2020
brain form in the shape of white flowers on black background with the striatum in red

Striatum, the brain’s reward hub, may drive core autism traits

by  /  17 February 2020

Associated primarily with its role in movement, the striatum may also influence the social difficulties of autistic people.

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November 2019
Portrait of Geraldine Bliss and her son Charles

New family group pursues treatments for autism-linked syndrome

by  /  19 November 2019

After a decade of working with the Phelan-McDermid Syndrome Foundation, Geraldine Bliss has co-founded a new organization to develop therapies for the condition.

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October 2019

Unusual gait marks mice with mutations related to autism

by  /  20 October 2019

Mouse models of two genetic conditions related to autism show abnormalities in their movement patterns.

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Skew in neuron numbers may explain sensory sensitivity in autism

by  /  20 October 2019

Loss of certain neurons on one side of the brain may explain why some autistic people are hypersensitive to touch.

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White rice in cage

Testing gene therapy for autism in mice? Consider your controls

by  /  3 October 2019

Deleting the mutation from an autism gene may reverse some autism traits in mice, according to a new study. But the results may be a fluke.

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June 2019
Video of three mice running on a wheel

Mechanical tracker measures social activity of multiple mice for days

by  /  28 June 2019

A new system enables researchers to automatically track the social behavior of up to four mice for days at a time.

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children standing in a line, oldest to youngest

Timing of autism treatments may be key to their success

by  /  20 June 2019

The timing of treatment is crucial for conditions related to autism — and more so for some conditions than for others.

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fMRIs of monkey brains in a grid of 6 show highlighted areas.

Monkeys with autism mutation show condition’s key traits

by  /  12 June 2019

Researchers have engineered two generations of monkeys with mutations in SHANK3, a top autism gene. The first generation shows traits reminiscent of the condition.

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May 2019
Young girl sleeping in the bed

Sleep struggles in autistic people may have genetic basis

by  /  3 May 2019

Autistic children may be more likely than their unaffected siblings to carry mutations in genes linked to sleep.

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February 2019

Drugs that modify gene expression show promise for autism

by  /  28 February 2019

An experimental compound that blocks two enzymes involved in gene expression improves social behavior in young mice.

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