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Tag: SHANK3

August 2015
News

Blinking mice bolster cerebellum’s link to autism

by  /  14 August 2015

Mice carrying any one of five autism-linked mutations struggle to associate a flash of light with an irritating puff of air. The findings suggest that the mice have trouble integrating information from multiple senses — a skill governed by the cerebellum.

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June 2015
News

Cell skeleton breakdown may spur autism symptoms in mice

by  /  15 June 2015

An autism-linked mutation in the SHANK3 gene alters the protein skeleton of mouse neurons. Repairing the scaffold eases the animals’ social deficits.

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May 2015
News

Oxytocin sails into trials for Phelan-McDermid syndrome

by  /  14 May 2015

The hormone oxytocin is proceeding into clinical trials for people with the autism-linked disorder Phelan-McDermid syndrome, researchers revealed yesterday at the 2015 International Meeting for Autism Research in Salt Lake City, Utah.

4 Comments
February 2015
Week of FebruaryFeb
9th
2015
News / Spotted

Spotted: Maladjusted foals; Kanner controversy

by  /  13 February 2015

Some newborn horses have features of autism, and researchers argue over who first described the disorder.

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December 2014
News / Toolbox

Method isolates protein complexes from neuronal junctions

by  /  17 December 2014

Researchers have for the first time isolated and characterized protein complexes found at the points of connection between neurons. Mutations in some of these proteins are linked to autism.

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November 2014
News

Takeaways from SfN 2014

by  /  20 November 2014

Scientists reflect on the current state of autism research as the 2014 Society for Neuroscience annual meeting in Washington, D.C. comes to a close.

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Opinion / Q&A

Questions for Thomas Insel: Paths to treatments for autism

by  /  18 November 2014

Finding people who have an autism-linked mutation but no apparent symptoms may be the key to identifying drug targets for the disorder, says Thomas Insel, director of the National Institute of Mental Health.
 

16 Comments
News

Family of autism-linked proteins helps neurons communicate

by  /  16 November 2014

The SHANK family of proteins, some of which are strong autism candidates, work together to facilitate brain signaling, according to unpublished results presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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News

Variants of autism-linked gene have diverse effects in mice

by  /  14 November 2014

Each of four different mutations in SHANK3, a leading autism candidate gene, leads to a different set of symptoms in mice, researchers have found. They presented their unpublished results on Thursday.

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News

Reactions from SfN 2014

by  /  14 November 2014

Tune in for daily updates and reactions from attendees at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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