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Tag: SHANK3

June 2016
News

Mice missing key autism gene hint at new treatment target

by  /  16 June 2016

A newly created strain of mice lacking SHANK3 closely mimics the effects of the protein’s loss in some people with autism.

1 Comment
News

Autism’s social problems may stem from sense of touch

by  /  9 June 2016

The anxiety and trouble with social skills seen in people with autism may originate outside of the brain, in neurons that govern touch.

1 Comment
April 2016
News

New role for autism gene extends treatment possibilities

by  /  11 April 2016

The autism-linked gene SHANK3 is known for its role at neuronal junctions, but it has another function that could serve as a drug target.

1 Comment
March 2016
News

Reports of neuron loss in autism may be exaggerated

by  /  17 March 2016

A widely used technique for identifying subtypes of neurons in the brain may be flawed, and may have provided incorrect tallies of a key neuron type in autism.

7 Comments
Opinion / Q&A

Questions for Thomas Bourgeron: In search of ‘second hits’

by  /  1 March 2016

Taking a close look at people who have a mutation in a known autism gene may reveal why these people often have vastly different characteristics.

5 Comments
February 2016
News

Mouse study offers promise of reversing autism symptoms

by  /  19 February 2016

Treatments for autism might be effective even after the brain is fully formed.

45 Comments
January 2016
News / Toolbox

Electrode-laced plates capture patterns of neural firing

by  /  27 January 2016

Growing neurons on tiny plates studded with miniature electrodes allows researchers to map patterns of neuronal activity within circuits.

1 Comment
News

Neighboring mutations in gene may spawn separate conditions

by  /  25 January 2016

Two seemingly similar mutations in the SHANK3 gene have divergent effects on the brain and behavior.

1 Comment
October 2015
News

Differences between rodents show limitations of models

by  /  20 October 2015

The same autism-linked mutation can lead to dramatically different behaviors in rats and mice.

0 Comments
News

On monkey island, some animals carry autism-linked mutation

by  /  20 October 2015

Roughly one-sixth of the monkeys on an island off the coast of Puerto Rico may carry a variant in SHANK3, a top autism gene candidate.

0 Comments