A brain region that orchestrates responses to social cues and aids decision-making may be off tempo in autism.

Many countries in Europe are reckoning with the growing demand for genetic tests for autistic people — and the accompanying ethical and scientific considerations.

This article is also available in anglais. Il y a quelques années la mère d’un jeune autiste m’a téléphoné. Elle venait d’apprendre que son fils, qui était dans la vingtaine, avait une délétion de SHANK3, l’un des gènes qui, d’après les découvertes de mon équipe, subit une mutation chez certaines personnes autistes. Cette nouvelle m’a […]

This year’s list of top papers highlights new dimensions in our understanding of autism genetics and hints at novel treatments.

The first monkey with a mutation in SHANK3, a top autism gene, is nearly 3; it spends its days circling its cage rather than interacting with other monkeys.

A team of researchers is trialing a fast approach to autism drug development: simultaneously testing candidates in people and in mice.

The pattern of high-pitched calls a mouse makes may reflect how, and how much, it is interacting with other mice. The pattern holds for typical mice as well as for two mouse models of autism.

Mapping the effects of autism mutations on mouse brain circuits may reveal subtypes of the condition in people.

People with mutations in SHANK3 have milder features than do those missing a chunk of DNA that includes the gene.

A prospective study shows that antipsychotics mess up metabolism, autism is tied to a doubled risk for food allergies, and a report reveals pervasive sexual harassment in science.