Matchmaking site for genes leads scientists to autism candidate
A website called GeneMatcher has helped researchers identify a new gene for intellectual disability, developmental delay and autism.
A website called GeneMatcher has helped researchers identify a new gene for intellectual disability, developmental delay and autism.
A new computational method sifts true mutations from spurious ones in a single cell’s genome.
One of the leading theories of autism posits that girls and women are biologically protected from the condition.
Finding a mutation linked to autism traits can have life-changing consequences for autistic individuals and their families.
Genetic tests for people with autism are far from routine and don’t always yield results, but the information they offer can change lives.
In autism research, as in other fields, small sample sizes can lead to false findings. The size of the sample needed for statistical significance depends on the type of study.
Genetic variants across the genome contribute to about 8 percent of the risk for certain developmental conditions — much more than previously thought.
Variants that control gene expression are often involved in whether a mutation ends up being harmful, and how harmful it is.
Software to identify genetic variants, along with a new synthetic human genome, could help scientists discover mutations associated with conditions such as autism.
Watch the complete replay of this journal club, which featured a paper exploring rare genetic variation in psychiatric conditions, including autism.