Tag: rare variants

June 2017
Opinion / Viewpoint

Genetics for poets

by  /  27 June 2017

Where do we stand in our understanding of autism genetics — and what major questions remain? A molecular biologist supplies answers in stanzas.

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News

Autism genetics, explained

by  /  27 June 2017

The more scientists dig into DNA, the more intricate its contribution to autism seems to be. Here, we unravel the complex genetics of autism.

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Opinion / Viewpoint

Family groups play key role in advancing autism research

by  /  27 June 2017

Families need more support from researchers in order for their heroic efforts to be optimally effective.

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Opinion / Viewpoint

Why it’s time to spin autism genes into drug screens

by  /  27 June 2017

Autism researchers’ top priority should be shifting their focus to finding treatments for severe forms of the condition.

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Opinion / Viewpoint

The interplay of common, rare variation in autism

by  /  27 June 2017

Autism researchers should ditch the false dichotomy between common inherited variants and much rarer random mutations.

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Opinion / Columnists / Gene jockey

Burning debate: What’s the best way to nab real autism genes?

by  /  27 June 2017

How to best use a large volume of data to discover new genetic risk factors for autism is a matter of intense debate, particularly in light of historical challenges.

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May 2017
News

Common variants, rare mutations combine to shape autism risk

by  /  15 May 2017

Children with autism inherit a greater burden of common genetic variants associated with autism than would be expected by chance. These variants combine with rare, spontaneous mutations to boost autism risk.

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News

What makes a gene an autism candidate? Not everyone agrees

by  /  11 May 2017

Whether a gene should be considered a ‘novel candidate’ for autism depends not just on whether it’s been linked to the condition before, but on the strength of that link.

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February 2017
News

Many people with harmful genetic variants show no ill effects

by  /  22 February 2017

Most adults with genetic variants tied to certain conditions, such as heart disease or cancer, go undiagnosed.

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News / Toolbox

Method reads brain cell signatures to reveal risky mutations

by  /  10 February 2017

A new approach ranks genes’ ties to autism based on their expression patterns in different types of brain cells.

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