Skip to main content

Spectrum: Autism Research News

Tag: rare variants

June 2017

The interplay of common, rare variation in autism

by  /  27 June 2017

Autism researchers should ditch the false dichotomy between common inherited variants and much rarer random mutations.

0 Comments

Burning debate: What’s the best way to nab real autism genes?

by  /  27 June 2017

How to best use a large volume of data to discover new genetic risk factors for autism is a matter of intense debate, particularly in light of historical challenges.

0 Comments
May 2017

Common variants, rare mutations combine to shape autism risk

by  /  15 May 2017

Children with autism inherit a greater burden of common genetic variants associated with autism than would be expected by chance. These variants combine with rare, spontaneous mutations to boost autism risk.

0 Comments

What makes a gene an autism candidate? Not everyone agrees

by  /  11 May 2017

Whether a gene should be considered a ‘novel candidate’ for autism depends not just on whether it’s been linked to the condition before, but on the strength of that link.

0 Comments
February 2017

Many people with harmful genetic variants show no ill effects

by  /  22 February 2017

Most adults with genetic variants tied to certain conditions, such as heart disease or cancer, go undiagnosed.

0 Comments

Method reads brain cell signatures to reveal risky mutations

by  /  10 February 2017

A new approach ranks genes’ ties to autism based on their expression patterns in different types of brain cells.

0 Comments
December 2016

Notable papers of 2016

by  /  26 December 2016

Our picks for the top 10 papers of the year highlight leaps in our understanding of autism, as well as lingering gaps.

1 Comment
November 2016
An illustration of two grandmothers conversing in front of a genealogical tree, suggesting ancestry and a history of autism in the family.

What grandmothers can teach scientists about autism’s inheritance

by  /  9 November 2016

Women who have raised a child with autism may be well-positioned to spot subtle signs of the condition in their grandchildren. A new study puts their powers to good use.

1 Comment
October 2016
A mutation in a human-specific DNA

Autism risk may originate in stretches of uniquely human DNA

by  /  6 October 2016

Mutations in certain newly evolved stretches of the genome may play a role in autism, although some experts are skeptical of this theory.

0 Comments
September 2016
Week of SeptemberSep
26th
2016

Spectrum of color; biased review; fees please

by  /  30 September 2016

Non-white adults with autism may feel forgotten, names on papers may bias peer reviewers, and eLife will begin charging publication fees.

0 Comments