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Spectrum: Autism Research News

Tag: gene expression

October 2019
micrographs of brain areas in red.

Drug counteracts effects of doubled autism gene

by  /  24 October 2019

An experimental drug tamps down the expression of a gene duplicated in an autism-related condition and restores typical behavior in mice.

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Two male finches sitting on roost in cage.

Protein linked to autism may help birds learn songs from elders

by  /  23 October 2019

Turning down the expression of a gene linked to autism leaves zebra finches singing disorganized songs.

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Maternal infection may accelerate expression of autism genes

by  /  21 October 2019

Exposure to infection in utero may speed up the expression of many genes linked to autism — and hasten changes in brain anatomy.

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DNA

Rapid assay flags autism mutations in regions that flank genes

by  /  21 October 2019

Researchers have identified mutations within regulatory regions that are likely to contribute to autism, using a speedy system of DNA ‘barcodes.’

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Strand of DNA with one base letter highlighted.

DNA technique documents key events in cell history

by  /  18 October 2019

A new method uses mutations in DNA to maintain a detailed record of series of cellular events.

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Brain ‘organoids’ point to new drug target for fragile X syndrome

by  /  18 October 2019

New findings hint at why drugs that work in mouse models of fragile X syndrome have not been effective in people.

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black and blue striped dress on pregnant woman shows DNA helix

Rare access to fetal tissue yields valuable insights into autism

by  /  15 October 2019

Molecular biologist Jonathan Mill is probing gene expression’s role in autism in uncharted territory — the fetal human brain.

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Study finds unexpected role for top autism gene

by  /  14 October 2019

SETD5, a leading candidate for autism risk, may control thousands of genes by modifying a protein involved in packaging DNA.

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September 2019
X chromosome with lots of contrasty texture inside, transparent outside

Genome structure unlikely to wield major influence on gene expression

by  /  27 September 2019

New findings call into question a fundamental assumption about how genes are regulated.

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colorful clusters of cells

Atlas of developing brain reveals rainbow of cell types

by  /  20 September 2019

An online resource reveals all major cell types in the developing human brain during the period in which autism is thought to arise.

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