In the spirit of Thanksgiving, those dealing with autism received some welcome news last week: The U.S. Food and Drug Administration approved Abilify (aripiprazole) as a treatment for autism-related irritability.
Spectrum: Autism Research News
Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.
Autism may be the result of faulty wiring that occurs during early brain development, according to two independent studies that looked at the origins of circuit disruption.
Deleting MeCP2, the gene that’s mutated in Rett syndrome, alters both the size and function of neurons in the mouse brain — at least in one brain region, the locus ceruleus — according to a 30 September report in the Journal of Neuroscience.
Giving mouse models of Rett syndrome access to toys, wheels and contact with other mice rescues motor skill and other deficits characteristic of the disorder, according to results presented in a poster session Wednesday at the Society for Neuroscience meeting in Chicago.
Deleting a neuronal protein associated with autism causes oxidative stress — characterized by an excess of free radicals — which has been linked to diseases such as diabetes and Alzheimer’s, according to new research in worms. The results were presented yesterday at a poster session at the Society for Neuroscience meeting in Chicago.
Mice missing FKBP12, a gene involved in a cancer pathway, show repetitive behavior and an impaired ability to socialize with other mice, and could be used to study autism, according to unpublished results presented at a poster session today at the Society for Neuroscience meeting.
A common variant of a gene called CACNA1G — which makes a channel that helps regulate calcium flow between cells — may increase the risk of developing autism, according to research published in Molecular Psychiatry.
Applying an emerging technique that combines genetic data and brain scans, researchers have identified two new genes involved in schizophrenia. The method, called ‘imaging genetics’, holds promise for linking genes to brain function in complex psychiatric disorders, including autism.