Seaside Therapeutics has announced results from a phase II clinical trial showing that, in children with autism, STX209 lowers agitation, tantrums, irritability and social withdrawal.

A decade ago, children with disabilities were almost always separated into their own rooms — or even buildings — with specialized teachers and lessons. But some research since then has shown that many of these children can learn well alongside healthy children, and vice versa.

The amygdala, a brain region that regulates fear and anxiety, shows abnormal neuronal signaling in a mouse model of fragile X syndrome, according to two studies published this summer. These are the first to explore cellular defects in the region in fragile X.

People with autism are asserting their right to be different. They say so-called ‘neurotypicals’ are the ones with communication problems, relying on the ‘animalistic means’ of body language, and they don’t understand why their focused, repetitive behaviors are thought to be problematic when neurotypicals indulge in obsessions such as sports and soap operas.

Mouse models of fragile X syndrome show defects in two kinds of potassium channels — ubiquitous pores that control the flow of electrical current across neurons — in a brain area that processes sound, according to two papers published this summer.

You’ll never hear Jacqueline Crawley talk about an ‘autistic mouse’. In fact, in her keynote address at IMFAR in May, she implored the audience to never use those two words in the same sentence.

If you believe the hype about oxytocin, it’s nothing short of a wonder drug: it can make you trust a stranger, enhance a mother’s bond with her child and, according to a study published earlier this year, improve social skills in individuals with autism. But look more closely, and there is ample cause for caution.

With robust training in developmental psychology and a techie’s fervor for new tools, Kevin Pelphrey is systematically investigating how the brain changes during development — starting in infants as young as 6 weeks old.

In the not-too-distant future, we may be able to diagnose toddlers with autism using a simple clinical test — based on voice patterns, blood or even urine.

Not all stem cells are created equal, a string of new studies suggests: adult cells that are reprogrammed into stem cells carry chemical remnants of the tissue from which they originate, making them distinct from embryonic stem cells. These differences may have important implications for studying fragile X syndrome and other diseases that arise from epigenetic glitches.