TOPIC

Treatments

Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.

Features / Deep Dive

Rethinking repetitive behaviors in autism

by  /  25 November 2019
Autistic people have long maintained that repetitive behaviors are beneficial. Emerging evidence in support of this idea is shaping new therapies.
News

Drug combination mutes sensitivity to noise in autism mice

by  /  25 November 2019
A mix of two drugs eases hypersensitivity to noise in mice missing an autism gene — offering the promise of a similar treatment for autistic people.
News

Mouse study reveals overlooked target for autism therapies

by  /  20 November 2019
Blocking one form of an enzyme implicated in autism eases unusual behaviors and seizures in mice missing a top autism gene.
November 2019
Portrait of Geraldine Bliss and her son Charles
Opinion / Q&A

New family group pursues treatments for autism-linked syndrome

by  /  19 November 2019

After a decade of working with the Phelan-McDermid Syndrome Foundation, Geraldine Bliss has co-founded a new organization to develop therapies for the condition.

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October 2019
Choosing between two plates: on the left, salmon and on the right, supplements.
News

Analysis finds little evidence to support dietary interventions for autism

by  /  28 October 2019

Special diets that eliminate certain foods or contain added supplements have minimal impact on autism traits, according to a review of 27 clinical trials.

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micrographs of brain areas in red.
News

Drug counteracts effects of doubled autism gene

by  /  24 October 2019

An experimental drug tamps down the expression of a gene duplicated in an autism-related condition and restores typical behavior in mice.

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News

Mouse study hints at why fragile X drugs fail in trials

by  /  22 October 2019

Drug after drug has failed in clinical trials for fragile X syndrome. A new study provides an explanation — a decrease in the drugs’ effectiveness over time — and points to a new strategy that could circumvent this problem.

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Marijuana plant
News

Cannabis compound improves sociability in autism mouse model

by  /  22 October 2019

A single dose of cannabidiol, a component of marijuana, eases seizures and improves learning and sociability in mice with mutations in an autism gene called CDKL5.

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linked hands in a pattern intertwined with DNA showing some broken parts, symbolizing mutations
News

Rett syndrome’s link to autism, explained

by  /  21 October 2019

Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.

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Opinion / Viewpoint

Angelman syndrome’s silent gene points way forward for autism therapies

by  /  21 October 2019

Advances in research and help from families have brought scientists to the brink of an effective therapy for Angelman syndrome.

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two young people in conversation
News

Computer games could boost social skills in people with autism

by  /  21 October 2019

Playing games designed to hone the ability to intuit others’ thoughts and feelings increases activity in regions of the social brain.

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News

CRISPR therapy may reverse autism mutation’s effects well past infancy

by  /  20 October 2019

Injecting the gene-editing tool CRISPR into the brains of mice may reverse the effects of an autism mutation at any age.

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RNA, transcription
News

Antidote to ‘poison’ DNA may treat lethal form of epilepsy

by  /  18 October 2019

An experimental drug silences a DNA segment and seems to prevent seizures and death in a condition related to autism.

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