TOPIC

Environment

From parental age to infection during pregnancy, environmental elements can influence autism risk.

November 2009
News

Only subset of chromosome 16 variants linked to autism

by  /  20 November 2009

Deletions or duplications of chromosomal segment 16p11.2 — previously reported as a key autism region — are seen in people with developmental delays and speech and behavioral problems, but not necessarily autism. That’s the finding from two large studies published last week of people carrying these rare genetic variations.

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October 2009
Opinion

Lessons from an obscure tumor

by  /  28 October 2009

There are well-established paternal age effects in diseases less common than autism. A new paper in Nature Genetics explains how the effects might arise, and it involves a kind of tumor you’ve probably never heard of.

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News

Enriched environment improves symptoms of Rett

by  /  23 October 2009

Giving mouse models of Rett syndrome access to toys, wheels and contact with other mice rescues motor skill and other deficits characteristic of the disorder, according to results presented in a poster session Wednesday at the Society for Neuroscience meeting in Chicago.

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News

Antibodies to fetal proteins trigger autism features

by  /  21 October 2009

Antibodies directed against the fetal brain are present in some mothers of children with autism, confirming previous findings and suggesting that the antibodies could be used as a marker for the disorder, according to unpublished research presented yesterday at the Society for Neuroscience meeting in Chicago.

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News

Postmortem study hints at two types of autism

by  /  21 October 2009

The brains of people with autism show high levels of inflammation compared with controls, suggests a study of postmortem brain tissue from 11 individuals with autism, presented at a poster session Monday at the Society for Neuroscience meeting in Chicago.

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News

Immune activation triggers autism features in mice

by  /  20 October 2009

Mice carrying an autism-associated mutation show impaired social interactions and dramatic changes in brain size when their immune systems are activated, according to research presented yesterday at a poster session at the Society for Neuroscience meeting in Chicago.

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News

Video: “Bad” autism animal models

by  /  18 October 2009

Tracy Bale, associate professor of neuroscience at the University of Pennsylvania, talks about what she calls her “big soapbox issue”: the fallacious idea of a true animal model for a human psychiatric disease — and the pitfalls of over-interpreting rodent behavior.

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September 2009
News / Profiles

Michael Wigler: Applying simple logic to complex genetics

by  /  18 September 2009

Interested more in ideas than in dominating a crowded field, Michael Wigler decided to apply his expertise in cancer genetics to studying poorly understood features of autism.

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August 2009
News

New autism risk genes may bolster fetal testosterone theory

by  /  25 August 2009

A team of British researchers has garnered some of the first genetic evidence supporting their theory that sex hormones play a role in the development of autism.

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News

Study raises questions about autism-gut connection

by  /  18 August 2009

Children with autism are no more likely than healthy children to have some of the gastrointestinal symptoms — such as diarrhea, acid reflux and abdominal discomfort — previously tied to the disorder, according to one of the first long-term investigations of the supposed link.

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