TOPIC

Environment

From parental age to infection during pregnancy, environmental elements can influence autism risk.

August 2010
News

Fragile X models give clues to stem cell programming

by  /  9 August 2010

Not all stem cells are created equal, a string of new studies suggests: adult cells that are reprogrammed into stem cells carry chemical remnants of the tissue from which they originate, making them distinct from embryonic stem cells. These differences may have important implications for studying fragile X syndrome and other diseases that arise from epigenetic glitches.

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July 2010
Opinion

Obsessive mice

by  /  21 July 2010

The biology of obsessive-compulsive disorder becomes even more baffling with the release of two new mouse models, each implicating a different type of brain cell.

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News

Study finds weak genetic link between autism and intelligence

by  /  20 July 2010

Autism and intellectual disability often occur together, but in most cases that overlap is not genetic, according to a study of twin pairs published in the American Journal of Medical Genetics. Unraveling this link might help researchers pinpoint brain circuits involved in both conditions, and better understand the diversity of symptoms in the autism spectrum, experts say.

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News

Deep sequencing questions role of imprinted genes in autism

by  /  8 July 2010

The mouse brain has more than 1,300 regions for which the copy from one parent is expressed more often than the one from the other parent, according to two studies published today in Science. These so-called imprinted genes have been proposed to cause some cases of autism, but the researchers say their findings do not support that theory.

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June 2010
News

Flu triggers schizophrenia-like features in monkeys

by  /  25 June 2010

Babies born to rhesus monkeys infected with the flu virus during pregnancy have significantly smaller brains than normal, and other brain abnormalities seen in schizophrenia, researchers have found. The study, published last month in Biological Psychiatry, provides the first evidence in non-human primates linking flu infection to a higher risk of schizophrenia.

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News

Rett gene function extends beyond neurons, study finds

by  /  15 June 2010

Microglia, brain cells that provide immune protection to neurons, may influence the onset and course of Rett syndrome, according to a study published in the Journal of Neuroscience.

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News

Worms set to fill holes in autism research

by  /  14 June 2010

Worms, despite their crude nervous system, can be useful models of the genetic underpinnings of autism, according to unpublished work presented today at a meeting of the Genetics Society of America in Boston.

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May 2010
News

Williams syndrome precludes racial bias, study finds

by  /  20 May 2010

Children with Williams syndrome — a rare genetic disorder that leads to mental retardation and overt friendliness — hold stereotypes based on gender, but not race, according to a report published in Current Biology. Because those with Williams syndrome don’t have social fear, the study suggests racial stereotypes are based partly on fear.

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Opinion

Granny’s genes

by  /  19 May 2010

The older a grandmother was when she bore her grandchild’s mother, the greater the child’s risk of autism, according to a study published last month in PLoS One.

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News

New technique maps methylated DNA

by  /  14 May 2010

A new technique can simultaneously sequence DNA and pinpoint some of the chemical modifications that turn genes on or off, according to a report published 9 May in Nature Methods. In particular, the technique reveals methyl groups bound to DNA bases.

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