TOPIC

Environment

From parental age to infection during pregnancy, environmental elements can influence autism risk.

September 2010
News

Studies tie fragile X syndrome to famous cancer pathway

by  /  23 September 2010

A drug that interferes with a biochemical pathway important in cancer can reverse some brain defects in mouse models of fragile X syndrome, according to a study published 11 August in the Journal of Neuroscience.

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Opinion

The power of talk

by  /  21 September 2010

In order to understand the interaction between genes and environment in autism, researchers in different disciplines will have to move back and forth between those two realms, stretching out of their intellectual comfort zones. But if the mood at an interdisciplinary workshop two weeks ago is any indication, that challenge is also a source of excitement.

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August 2010
News

Social factors may drive the spike in autism cases

by  /  27 August 2010

Changes in diagnostic practices, more active neighborhood networks, and an increase in the number of older parents may all contribute to the massive rates of autism in California, says a group of social scientists. But the numbers still don’t add up.

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News

Norway baby study expected to yield insights into autism

by  /  20 August 2010

The Autism Birth Cohort, based on data from 100,000 Norwegian children and their families, aims to uncover genetic and environmental factors contributing to the disorder.

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News

Brain’s adaptability begins at single synapse

by  /  10 August 2010

Researchers have uncovered an important molecular piece of a learning mechanism that occurs at the junction between neurons. The findings, which may help understand how the brain is disrupted in disorders such as autism, appear in the 24 June issue of Neuron.

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Opinion

Simple screens

by  /  10 August 2010

In the not-too-distant future, we may be able to diagnose toddlers with autism using a simple clinical test — based on voice patterns, blood or even urine.

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News

Fragile X models give clues to stem cell programming

by  /  9 August 2010

Not all stem cells are created equal, a string of new studies suggests: adult cells that are reprogrammed into stem cells carry chemical remnants of the tissue from which they originate, making them distinct from embryonic stem cells. These differences may have important implications for studying fragile X syndrome and other diseases that arise from epigenetic glitches.

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July 2010
Opinion

Obsessive mice

by  /  21 July 2010

The biology of obsessive-compulsive disorder becomes even more baffling with the release of two new mouse models, each implicating a different type of brain cell.

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News

Study finds weak genetic link between autism and intelligence

by  /  20 July 2010

Autism and intellectual disability often occur together, but in most cases that overlap is not genetic, according to a study of twin pairs published in the American Journal of Medical Genetics. Unraveling this link might help researchers pinpoint brain circuits involved in both conditions, and better understand the diversity of symptoms in the autism spectrum, experts say.

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News

Deep sequencing questions role of imprinted genes in autism

by  /  8 July 2010

The mouse brain has more than 1,300 regions for which the copy from one parent is expressed more often than the one from the other parent, according to two studies published today in Science. These so-called imprinted genes have been proposed to cause some cases of autism, but the researchers say their findings do not support that theory.

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