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Spectrum: Autism Research News

Tag: fragile X syndrome

June 2011

Protein networks link different forms of autism, study says

by  /  13 June 2011

Researchers have identified hundreds of previously unknown connections between proteins involved in autism spectrum disorders, according to a report published last week in Science Translational Medicine.

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Top of the class

by  /  10 June 2011

A drug called arbaclofen has matriculated to a phase III clinical trial, the last and most difficult step on the long road to regulatory approval.

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Solving the complex causes of a multi-hit disorder

by ,  /  7 June 2011

What’s known about the genetics of autism supports the ‘snowflake’ hypothesis — that the molecular underpinnings of disease are essentially unique from individual to individual — says human geneticist Brett Abrahams.

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May 2011

Cognition and behavior: Drug enhances social learning

by  /  27 May 2011

A compound that activates a pathway related to learning and memory can enhance pair-bonding between prairie voles, according to a study published 7 April in Biological Psychiatry. Enhancing social learning — an individual’s response to social cues — during development could help treat autism.

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Isabelle Rapin: Lessons from my clinic

by  /  24 May 2011

Autism is diagnosed based on the severity and variety of its symptoms. This makes it very difficult to diagnose and easy to confuse with other disorders, such as language delay and intellectual disability, cautions Isabelle Rapin.

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Genetics: Pathway links autism, intellectual disability

by  /  18 May 2011

Individuals with intellectual disability are more likely than controls to have harmful mutations in autism candidate genes, according to a study published 11 March in the American Journal of Human Genetics.

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Scientists probe puzzling overlap of epilepsy and autism

by  /  12 May 2011

Large studies on the epidemiology and genetics of epilepsy and autism have uncovered commonalities between the two disorders. But scientists are only beginning to untangle the biological roots of the overlap.

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Trendsetters

by  /  6 May 2011

Of 72 newly elected members of the National Academy of Sciences, 7 work either directly on autism or in related areas, illustrating the growing intellectual breadth and depth of the field.

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April 2011

Molecular mechanisms: Mice lacking MET have strong brain connections

by  /  26 April 2011

Mice missing the autism candidate gene MET have connections in the cortex that are twice as strong as those in controls, according to a new study.

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Genetics: New autism mouse reveals candidate gene

by  /  6 April 2011

A new mouse model for autism has obsessive behaviors and is less social and emits fewer vocalizations than controls, according to a study published 17 March in Behavioral Brain Research. These features could be be the result of much higher levels of FAM46, a gene of unknown function that may be involved in signaling between cells.

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