Tag: fragile X syndrome

May 2010
News / Toolbox

Creatures great and small

by  /  18 May 2010

Among animal models of autism, the mouse reigns supreme. But could much simpler species — flies, bees, worms, fish — also teach us about the disorder?

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News

Mouse models reveal workings of neuroligin-1

by  /  4 May 2010

Researchers are tinkering with mouse models to investigate the function of a protein that helps wire neurons together and that has repeatedly been linked to autism. Three such reports of the protein, neuroligin-1, have appeared this year.

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April 2010
News

Scientists find molecular player in Angelman syndrome

by  /  27 April 2010

Two independent teams have discovered key molecular steps in the way a single gene disrupts the connections between neurons in individuals with Angelman syndrome. Because the gene, UBE3A, has also been linked to autism, the findings could help scientists understand and treat a range of neurodevelopmental disorders.

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March 2010
News

Autism and fragile X feature immune signatures

by  /  30 March 2010

Scientists have identified distinct blood signatures of cytokines — proteins that control communication between cells of the immune system — in individuals with fragile X syndrome and autism.

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News

Delay found in development of fragile X brains

by  /  26 March 2010

Young mouse models of fragile X syndrome show a significant lag in the development of synapses, the connections between neurons, according to a study published in Neuron. The findings suggest that a similar mistiming may be responsible for the sensory problems — such as hypersensitivity to touch and sound — sometimes seen in people with fragile X syndrome.

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Opinion

Learning opportunities

by  /  23 March 2010

There are several short periods during development in which our brains are ‘plastic’ — meaning that neuronal connections appear and disappear depending on how much they are used. Researchers may have found a way to reopen those learning windows.

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News / Profiles

Evan Eichler: Following his instincts to autism ‘hotspots’

by  /  22 March 2010

With an openness to collaboration and a healthy dose of daring, Evan Eichler has turned his offbeat interest in repeat DNA sequences into a new understanding of how genomes evolve, expediting the search for genes disrupted in autism.

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February 2010
News / Toolbox

Super-cool synapses

by  /  1 February 2010

A chilling new technique shows the intricate and coordinated activity of previously mysterious pieces of the synapse, the all-important junction between neurons that allows cells to talk to each other.

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December 2009
News

Pupil response to light could be biomarker for autism

by  /  11 December 2009

The pupils of children with autism contract more slowly in response to flashes of light than those of their healthy peers, according to findings published in the November issue of the Journal of Autism and Developmental Disorders.

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Opinion

Approving news

by  /  4 December 2009

In the spirit of Thanksgiving, those dealing with autism received some welcome news last week: The U.S. Food and Drug Administration approved Abilify (aripiprazole) as a treatment for autism-related irritability.

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