Minocycline, an antibiotic approved to treat various infections including acne, can increase vocalizations and provide long-lasting improvements in anxiety in a fragile X mouse model, according to two posters presented at the Society for Neuroscience annual meeting in San Diego.
Lowering the levels of proteins associated with Alzheimer’s disease can improve symptoms of fragile X syndrome in mice, according to a poster presented Wednesday at the Society for Neuroscience annual meeting in San Diego.
Lithium ameliorates some of the cognitive and behavioral deficits associated with fragile X syndrome by blocking GSK-3, an enzyme that plays a key role in development, researchers said Wednesday at the Society for Neuroscience annual meeting in San Diego.
The brains of young mice with fragile X syndrome show a dearth of two proteins that are important at the synapse, the junction between neurons, researchers reported Tuesday at the Society for Neuroscience annual meeting in San Diego.
Contrary to popular belief, receptors both outside and inside a cell regulate a cellular pathway that is overactive in people with fragile X syndrome, researchers reported Tuesday at the Society for Neuroscience annual meeting in San Diego. The finding could have significant implications for drug treatments of fragile X syndrome.
A study of mice with tuberous sclerosis — a single-gene disorder that is related to autism — suggests that most forms of autism share a common feature: an imbalance of proteins at the synapse, the junction between neurons. The work was presented Monday at the Society for Neuroscience annual meeting in San Diego.
The brains of people with autism have abnormally dense and stubby dendritic spines, the neuronal projections that receive electrical signals, according to data presented Monday at the Society for Neuroscience annual meeting in San Diego.
The fruit fly is a good model for some of the cognitive defects in fragile X syndrome — but researchers sometimes find themselves having to defend their choice.
New DNA tests for fragile X syndrome are quick, but also raise ethical questions: they pick up abnormalities in some babies who won’t develop symptoms until adulthood, if at all.
A new wave of genetic tests for fragile X syndrome, the leading cause of inherited mental retardation and the most common genetic cause of autism, may make it possible to routinely screen pregnant women and newborns for the syndrome.