Mutations in the gene CSDE1 lead to a constellation of developmental delays and conditions, including autism, according to a new study.
Some traits of fragile X syndrome may be due to problems with mitochondria, the cell’s energy factories.
Drug after drug has failed in clinical trials for fragile X syndrome. A new study provides an explanation — a decrease in the drugs’ effectiveness over time — and points to a new strategy that could circumvent this problem.
A single seizure early in life leads to enduring behavioral problems, including diminished sociability, in mice.
New findings hint at why drugs that work in mouse models of fragile X syndrome have not been effective in people.
Researcher Randi Hagerman is a big proponent of metformin — a diabetes drug that she is testing in people with fragile X syndrome. In fact, Hagerman takes the drug herself as a preventive measure against cancer.
Watch the complete replay of Mark Bear discussing the latest research on treatments for fragile X syndrome.
Lovastatin, a drug that lowers cholesterol levels, prevents memory and learning problems in a rat model of fragile X syndrome.
About half of boys and men with fragile X syndrome injure themselves — and continue to do so for years.
The relatives of autistic people often have mild traits of the condition. Studying these family members could broaden our understanding of autism.