Tag: fragile X syndrome

December 2019
Features / Special Reports / 2019: Year in review

Five hot topics in autism research in 2019

23 December 2019

This year’s hot topics in autism research center around brain organoids, heart rate, the gut microbiome, treatment timing and early detection.

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October 2019
four panels show mouse neurons showing abnormalities
News

New gene linked to autism, neuron development

by  /  30 October 2019

Mutations in the gene CSDE1 lead to a constellation of developmental delays and conditions, including autism, according to a new study.

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Mitochondrion, coloured transmission electron micrograph (TEM). Mitochondria are a type of organelle found in the cytoplasm of eukaryotic cells. They oxidise sugars and fats to produce energy in a process called respiration. A mitochondrion has two membranes, a smooth outer membrane and a folded inner membrane. The folds of the inner membrane are called cristae, and it is here that the chemical reactions to produce energy take place. Magnification: x62,800 when printed at 10 centimetres wide.
News

Leaky mitochondria may play central role in fragile X syndrome

by  /  23 October 2019

Some traits of fragile X syndrome may be due to problems with mitochondria, the cell’s energy factories.

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News

Mouse study hints at why fragile X drugs fail in trials

by  /  22 October 2019

Drug after drug has failed in clinical trials for fragile X syndrome. A new study provides an explanation — a decrease in the drugs’ effectiveness over time — and points to a new strategy that could circumvent this problem.

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Two mice in a lab test environment
News

Single seizure may have long-lasting effects on brain

by  /  21 October 2019

A single seizure early in life leads to enduring behavioral problems, including diminished sociability, in mice.

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News

Brain ‘organoids’ point to new drug target for fragile X syndrome

by  /  18 October 2019

New findings hint at why drugs that work in mouse models of fragile X syndrome have not been effective in people.

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September 2019
Colorful figure with a circle shape (a pill) and an orange X in the background symbolizing Fragile X
Opinion / Q&A

Diabetes drug delivers multiple benefits for people with fragile X syndrome

by  /  17 September 2019

Researcher Randi Hagerman is a big proponent of metformin — a diabetes drug that she is testing in people with fragile X syndrome. In fact, Hagerman takes the drug herself as a preventive measure against cancer.

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August 2019
Portrait of Mark Bear
Multimedia / Webinars

Webinar: Mark Bear discusses fragile X syndrome, from bench to bedside

21 August 2019

Watch the complete replay of Mark Bear discussing the latest research on treatments for fragile X syndrome.

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June 2019
Statin pill rests on blister pack
News

Popular statin shows promise for treating fragile X syndrome

by  /  17 June 2019

Lovastatin, a drug that lowers cholesterol levels, prevents memory and learning problems in a rat model of fragile X syndrome.

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Young man sits alone with his hands over his face
News

Self-injury persists for years in boys with fragile X syndrome

by  /  5 June 2019

About half of boys and men with fragile X syndrome injure themselves — and continue to do so for years.

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