Mutations in the gene CSDE1 lead to a constellation of developmental delays and conditions, including autism, according to a new study.

Some traits of fragile X syndrome may be due to problems with mitochondria, the cell’s energy factories.

Drug after drug has failed in clinical trials for fragile X syndrome. A new study provides an explanation — a decrease in the drugs’ effectiveness over time — and points to a new strategy that could circumvent this problem.

A single seizure early in life leads to enduring behavioral problems, including diminished sociability, in mice.

New findings hint at why drugs that work in mouse models of fragile X syndrome have not been effective in people.

Lovastatin, a drug that lowers cholesterol levels, prevents memory and learning problems in a rat model of fragile X syndrome.

About half of boys and men with fragile X syndrome injure themselves — and continue to do so for years.