Genes implicated in Tourette syndrome overlap with those involved in autism, according to an analysis of rare DNA duplications and deletions in people with the syndrome, published in the March issue of Biological Psychiatry.
Researchers have uncovered cellular abnormalities in Timothy syndrome by regenerating neurons from individuals with the rare autism-related disorder, according to a study published 27 November in Nature Medicine.
Loss of MeCP2, the Rett syndrome gene, in neurons that release the chemical messenger dopamine may lead to the motor deficits associated with the syndrome.
Genetic variants in two autism-associated genes have been linked to repetitive behavior and hyperactivity, two common symptoms of the disorder, according to two studies published in the past few months.
Using tricks of genetic engineering, researchers in Taiwan have created the first comprehensive map of the myriad neuronal connections in the fruit fly brain. The findings appeared 11 January in Current Biology.
A combination approach may hold promise for treating repetitive motor behaviors, such as those seen in people with autism, according to research presented yesterday at the Society for Neuroscience annual meeting in San Diego.