Tag: dopamine

September 2013
News / Toolbox

Rats armed to catch up to mice as top mammalian model

by  /  4 September 2013

Researchers have developed a method to engineer rats so that they lack a certain gene in only select regions of the brain, they report in the July issue of Nature Methods.

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August 2013
Opinion

Ritalin reaction

by  /  23 August 2013

Some children with autism and hyperactivity have a genetic intolerance to methylphenidate (Ritalin), the drug commonly prescribed for attention deficit hyperactivity disorder, reports a new study published 16 July in Pharmacogenomics.

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June 2013
News

Genetics: Variants in chromosome 16 region show male bias

by  /  25 June 2013

Males, but not females, with neurodevelopmental disorders such as autism are more likely to have deletions or duplications in the 16p13.11 chromosomal region than controls are, according to a study published 18 April in PLoS One.

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April 2013
News / Toolbox

Miniature brain bulbs manipulate neurons

by  /  24 April 2013

A light-emitting device implanted in a mouse brain can activate neurons wirelessly, allowing researchers to control and observe the mouse’s behavior, according to a report published 12 April in Science.

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December 2012
News

Molecular mechanisms: Autism genes regulate cell sensors

by  /  18 December 2012

Genes involved in neuropsychiatric disorders tend to be required for the formation of primary cilia — small tentacles on the cell surface that sense the external environment — according to a study published 3 October in PLoS One.

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November 2012
News / Toolbox

Brain atlas maps gene expression in three dimensions

by  /  14 November 2012

Researchers have charted patterns of gene expression in a three-dimensional representation of the human brain. The results, published 20 September in Nature, show that different brain regions have distinct molecular and functional roles.

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October 2012
News

Study implicates ‘pleasure circuit’ in Angelman syndrome

by  /  18 October 2012

Mice that model Angelman syndrome, an autism-related disorder, are more motivated to earn rewards than controls are, according to unpublished results presented Wednesday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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News

Mice with autism-linked deletion show unexpected deficits

by  /  15 October 2012

Mice lacking one copy of the autism-linked 16p11.2 chromosomal region are thin, deaf and show repetitive behaviors. They also have altered proportions of neurons in their brains, particularly those that express the chemical messenger dopamine. The unpublished results were presented Sunday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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News

Molecular mechanisms: Angelman region affects serotonin

by  /  12 October 2012

Mice that model Angelman syndrome or have a duplication of the 15q11-13 chromosomal region have aberrant brain levels of the chemical messenger serotonin, according to a study published 16 August in PLoS One.

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April 2012
News / Toolbox

Chili pepper protein can alter behavior of mice

by  /  18 April 2012

By manipulating the location of a protein that detects capsaicin, the molecule responsible for the burn in hot chili peppers, researchers can activate subpopulations of neurons and alter the behavior of mice. The results were published 20 March in Nature Communications.

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