Tag: dopamine

November 2014
News / Toolbox

Sensors shed light on levels of chemical messengers in mice

by  /  12 November 2014

Cells modified to carry fluorescent sensors can help researchers detect the levels of various chemical messengers in the brains of living mice.

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August 2014
News / Toolbox

Deep-brain neurons’ glow reveals elements of social circuits

by  /  13 August 2014

Light-transmitting cables implanted deep in mouse brains reveal connections between brain regions that control social interactions, according to a study published 19 June in Cell.

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July 2014
Opinion / Viewpoint

Schizophrenia milestone holds lessons for autism

by  /  21 July 2014

A long-awaited report, published today in Nature, confirms that with access to tens of thousands of genomes, researchers can identify common genetic risk factors for a complex neuropsychiatric disorder.

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May 2014
News

Mice with chromosome 16 deletion have faulty brain circuits

by  /  26 May 2014

Researchers have linked defects in the dopamine brain circuit to behaviors of a new mouse model of the 16p11.2 deletion. In a study in the 16 May Cell Reports, they suggest that the mutation alters the brain’s regulation of dopamine and may be responsible for behavioral problems, including autism.

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April 2014
News

Risperidone use in children with autism carries heavy risks

by  /  28 April 2014

Risperidone, the first drug approved for children with autism and the most widely used, improves some children’s behavior but can have severe side effects, suggests an informal analysis of the drug’s use. 

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January 2014
News

Molecular mechanisms: Reward affects motor function in Rett

by  /  10 January 2014

The motor problems seen in Rett syndrome may be the result of deficits in a reward pathway in the striatum, according to a study published 12 November in Brain Structure and Function. 

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News

Mounting evidence implicates cerebellum in autism

by  /  6 January 2014

Results from four studies published in the past year point to a role for the cerebellum in autism-related behaviors.

8 Comments
November 2013
News / Toolbox

Miniature cable reads a mouse’s sense of reward

by  /  20 November 2013

A tiny fiber-optic probe inserted into the reward center of the mouse brain monitors how the mouse feels about meeting a peer — or a golf ball. The unpublished technique was presented last week at the 2013 Society for Neuroscience annual meeting in San Diego.

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News

Mouse models reveal Rett gene’s myriad effects

by  /  13 November 2013

MeCP2, the gene associated with Rett syndrome, has widely variable effects on mouse brains depending on the mutation it carries, according to unpublished results presented Tuesday at the 2013 Society for Neuroscience annual meeting in San Diego.

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News

Genetics: Spontaneous mutation links dopamine to autism

by  /  12 November 2013

A newly discovered spontaneous mutation, described 27 August in Molecular Psychiatry, links autism to changes in the regulation of the chemical messenger dopamine.

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