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Spectrum: Autism Research News

Tag: connectivity

December 2013

Charting typical brain development

by  /  20 December 2013

How can we characterize what is atypical when we don’t fully understand what typical brain development looks like, particularly under the age of 5? Christine Wu Nordahl explains the importance of scanning the brains of typically developing children.

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Colorful, computer-generated illustration of shapes and colors emanating from an open book.

Sense-jumbling synesthesia often accompanies autism

by  /  17 December 2013

Synesthesia, a condition in which people mix up different types of sensory stimuli, is nearly three times as common in adults with autism as in the general population, reports a study published 20 November in Molecular Autism.

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Understanding contradictory connectivity reports in autism

by ,  /  10 December 2013

Studies at the level of neural circuits are needed to better understand the importance of both increased and decreased connectivity between different regions in the autism brain, say John Rubenstein and Vikaas Sohal.

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Study seeks autism biomarkers in brain-imaging database

by  /  9 December 2013

A large, multisite dataset of brain scans identifies autism with 60 percent accuracy, much lower than the numbers cited by single-site studies. The study, published 25 September in Frontiers in Human Neuroscience, highlights the vast differences in equipment, quality and methods across sites.

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November 2013

More or less connected in autism, compared to what?

by  /  19 November 2013

Emerging findings in children with autism are showing both hyperconnectivity and underconnectivity in different regions and circuits throughout the brain.

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SfN 2013 comes to a close

by  /  18 November 2013

A packed week of research at the 2013 Society for Neuroscience annual meeting in San Diego brought a flurry of breaking news and a creative combination of emerging research tools.

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Resting-state maps bridge mouse models, humans

by  /  12 November 2013

Researchers have produced images of connectivity during resting-state activation, which occurs while individuals are resting quietly in a scanner, in mouse brains. The new technique was presented Monday at the 2013 Society for Neuroscience annual meeting in San Diego.

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Gender affects nerve fiber integrity in tuberous sclerosis

by  /  11 November 2013

Boys with tuberous sclerosis complex, an autism-related disorder, have more disorganized nerve fibers in some regions of the brain than do girls with the disorder, according to unpublished work presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.

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Brain’s immune cells boost rapid transmission of signals

by  /  11 November 2013

Two new studies bolster the emerging idea that microglia, cells that were long dismissed as passive soldiers of the brain’s immune system, are in fact actively involved in shoring up connections between neurons. The unpublished work was presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.

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Studies on 22q11.2 region link genes, circuits, behavior

by  /  10 November 2013

Deletion of a gene in 22q11.2, a chromosomal region linked to autism and schizophrenia, leads to small head size in mice, according to research presented Saturday at the 2013 Society for Neuroscience annual meeting in San Diego. Mice with a large deletion in this region show disrupted brain connections, and struggle with learning and memory.

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