Connectivity
Drafting a ‘dysfunctome’: Faulty connections to subthalamic nucleus characterize disparate brain disorders
Different circuits between the millimeters-wide structure and the cortex go awry in Tourette syndrome, obsessive-compulsive disorder, dystonia and Parkinson’s disease, a new study of human brain scans suggests.
Microglial overreaction to atypical neurons may drive autism
In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.
Microglial overreaction to atypical neurons may drive autism
Noisy brain may underlie some of autism’s sensory features
Random fluctuations in neuronal activity are more variable in a fragile X mouse model than in wildtype mice.
Noisy brain may underlie some of autism’s sensory features
Standout neuroscience news in 2023
Did you miss any of our favorite stories from the past year? Revisit them here.
What happens when a histopathologist teams up with computational modelers?
Answers emerge in my chat with Nicola Palomero-Gallagher, a rare example of someone who connects the brain’s microscopic constituents and macroscopic features.
What happens when a histopathologist teams up with computational modelers?
Plugging invisible gaps in the synaptic connectome
Two new maps of the roundworm nervous system detail how neurons communicate with short proteins called neuropeptides outside synapses.
Plugging invisible gaps in the synaptic connectome
Full connectome of adult fruit fly completed, with help from citizen scientists
The map, by far the largest one of an entire brain to date, contains 130,000 neurons and 53 million synapses.
Full connectome of adult fruit fly completed, with help from citizen scientists
Robotic headgear records brain activity in moving mice
The tool could help researchers study the neurobiology of natural behaviors, scientists say.
Robotic headgear records brain activity in moving mice
Repurposed electronics lens spies neurons across entire mouse brain
When combined with tissue-inflation methods, the microscope can image axons without the need for tissue slicing, the researchers say.
Repurposed electronics lens spies neurons across entire mouse brain
Statistical method improves behavioral predictions from fMRI
The framework, inspired by the polygenic risk score, considers the cumulative effect of neuronal connections.
Statistical method improves behavioral predictions from fMRI
Explore more from The Transmitter
Some minimally verbal autistic people show signs of written-language familiarity, study suggests
But researchers not involved in the work worry the findings could be used to support discredited facilitated-communication techniques.
Some minimally verbal autistic people show signs of written-language familiarity, study suggests
But researchers not involved in the work worry the findings could be used to support discredited facilitated-communication techniques.
Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.
Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.
X chromosome inactivation; motor difficulties in 16p11.2 duplication and deletion; oligodendroglia
Here is a roundup of autism-related news and research spotted around the web for the week of 6 May.
X chromosome inactivation; motor difficulties in 16p11.2 duplication and deletion; oligodendroglia
Here is a roundup of autism-related news and research spotted around the web for the week of 6 May.