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Spectrum: Autism Research News

Tag: brain size

May 2021
Microglia activity seen in red, green and blue.

Autism mutation may cause big brain via ‘don’t eat me’ signals

by  /  17 May 2021

An autism-linked mutation could make the brain grow unusually large by prompting cells to express a chemical signal better known for its connection to cancer.

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April 2021
Two views of mouse brain slices colorized in green and red.

Jump-starting growth signaling reverses microcephaly in autism mouse model

by  /  29 April 2021

A genetic therapy and an existing drug both restore typical brain size in mice missing DYRK1A, a top autism candidate gene, in the cerebral cortex, a new study shows. The animals typically have smaller brains than controls.

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Loss of CHD8 from cerebellum disrupts movements, not social behaviors

by  /  26 April 2021

Deleting the autism-linked gene CHD8 from specific cells in the cerebellum, a brain region important for movement, leads to motor deficits but does not alter social behaviors in mice.

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March 2021
Oligodendrocyte shown orange on black in this scanning electron micrograph.

How oligodendrocytes may shape autism

by  /  15 March 2021

A growing body of evidence shows that brain cells called oligodendrocytes may play a larger role in autism than previously thought.

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January 2021
Colorful CT scan of a zebrafish head.

Zebrafish strains reveal broad effects of autism genes

by  /  11 January 2021

Mutations in autism-linked genes lead to a variety of changes in brain activity, sensory perception and sleep-wake cycles in zebrafish.

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December 2020
Brain organoid with multiple stains; red and green, to indicate cells.

New method probes genes’ function in brain organoids

by  /  16 December 2020

A screening technique tests how inactivated genes affect spheres of cultured brain cells; it could shed light on autism-linked mutations.

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October 2020
four brain areas marked with flags: Cortex, amygdala, hippocampus, cerebellum

Brain structure changes in autism, explained

by  /  15 October 2020

Autistic people have distinct patterns of brain development, which sometimes result in differences in brain structure. Here’s what we know about those differences.

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August 2020
Illustration showing the human brain made out of flower shapes with the brainstem labeled.

Brain’s center of automatic body functions has autism links

by  /  20 August 2020

The brainstem controls such disparate functions as breathing, sensation and sleep — all of which can be altered in autism.

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July 2020
group of 4 brain views

Autistic people with rare mutation may have unique brain anatomy

by  /  17 July 2020

Brain structure of autistic people with deletions in the chromosomal region 22q11.2 differs from that of autistic people without the deletions.

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June 2020

Autism linked to sleep problems and brain changes in infancy

by  /  19 June 2020

Children with autism are more likely than typical children to have had problems falling asleep as infants, and to have shown brain overgrowth.

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