Some people with autism have an unusually large head. What causes the enlargement? And does it have any bearing on outcome?
Spectrum: Autism Research News
Tag: brain size
People with mutations in CHD8, a top autism gene, tend to be tall and have large heads.
A new analysis of nearly 40,000 people pinpoints 48 genetic variants that may determine the volume of certain brain areas.
Blocking one form of an enzyme implicated in autism eases unusual behaviors and seizures in mice missing a top autism gene.
Researchers have used the gene-editing tool CRISPR to disable the MECP2 gene in marmoset embryos. The six such marmosets created seem to recapitulate aspects of Rett syndrome.
Delivery by cesarean section leads to subtle brain and behavioral alterations in mice, particularly those delivered prematurely.
The severity of autism tracks closely with that of attention deficit hyperactivity disorder.
The loss of 21 genes on chromosome 3 may substantially raise the risk of autism.
Any study of postmortem brains must control for artifacts, which are pervasive in brain tissue.